Influenza remains one of the most significant public health threats due to its ability to cause
high morbidity and mortality worldwide. Although understanding of influenza viruses has …

The use of these different platforms for antibody delivery has been demonstrated across a
wide range of animal models and disease indications, including HIV. Although each …

The pig is an important agricultural species and powerful biomedical model. We have
established the pig, a large natural host animal for influenza with many physiological …

In the light of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic,
we have developed a porcine respiratory coronavirus (PRCV) model for in depth …

The porcine respiratory disease complex (PRDC) is responsible for significant economic
losses in the pig industry worldwide. Porcine reproductive and respiratory syndrome virus …

Simple Summary Macrophages play a central role in innate immune response to both
infectious and non-infectious stressors. They respond to different agonists modifying their …

We have used the pig, a large natural host animal for influenza with many physiological
similarities to humans, to characterize αβ, γδ T cell and antibody (Ab) immune responses to …

For the first time we have defined naïve, central memory, effector memory and differentiated
effector porcine CD8 T cells and analyzed their distribution in lymphoid and respiratory …

A vaccine providing both powerful Ab and cross-reactive T cell immune responses against
influenza viruses would be beneficial for both humans and pigs. In this study, we evaluated …

Swine are attracting increasing attention as a biomedical model, due to many immunological
similarities with humans. However, porcine macrophage polarization has not been …