Neuropathic pain is a common and debilitating modality of chronic pain induced by a lesion
or disease of the somatosensory nervous system. Albeit the elucidation of numerous …

Eukaryotic cells engage in autophagy, an internal process of self-degradation through
lysosomes. Autophagy can be classified as selective or non-selective depending on the way …

Background Zishenhuoxue decoction (ZSHX), a Chinese herbal medicine, exhibits
myocardial and vascular endothelial protective properties. The intricate regulatory …

Mitochondria play a key role in cancer and their involvement is not limited to the production
of ATP only. Mitochondria also produce reactive oxygen species and building blocks to …

How to address the resistance of cisplatin (CDDP) has always been a clinical challenge.
The resistance mechanism of platinum-based drugs is very complex, including nuclear DNA …

Background Mitochondrial dysfunction and metabolic reprogramming can lead to the
development and progression of hepatocellular carcinoma (HCC). Ferredoxin 1 (FDX1) is a …

Nanoplastics (NPs) are defined as a group of emerging pollutants. However, the adverse
effect of NPs and/or heavy metals on mammals is still largely unclear. Therefore, we …

Oxygen therapy is common during the neonatal period to improve survival, but it can
increase the risk of oxygen toxicity. Hyperoxia can damage multiple organs and systems in …

As a novel antioxidant, a growing body of studies has documented the diverse biological
effects of molecular hydrogen (H2) in a wide range of organisms, spanning animals, plants …

Mitophagy, a form of selective autophagy that removes damaged or dysfunctional
mitochondria, plays a crucial role in maintaining mitochondrial and cellular homeostasis …