H Oliveri, A Goriely - Biomechanics and Modeling in Mechanobiology, 2022 - Springer
The establishment of a functioning neuronal network is a crucial step in neural development. During this process, neurons extend neurites—axons and dendrites—to meet other neurons …
Abstract Development of a biomimetic tubular scaffold capable of recreating developmental neurogenesis using pluripotent stem cells offers a novel strategy for the repair of spinal cord …
S Tang, J Zhu, Y Xu, AP Xiang, MH Jiang, D Quan - Biomaterials, 2013 - Elsevier
Introducing concentration gradients of nerve growth factor (NGF) into conduits for repairing of peripheral nerve injury is crucial for nerve regeneration and guidance. Herein, combining …
Microfluidic spatial and temporal gradient generators have played an important role in many biological assays such as in the analysis of wound healing, inflammation, and cancer …
H Zhu, C Yao, B Wei, C Xu, X Huang… - … Journal of Extreme …, 2023 - iopscience.iop.org
Abstract 3D printing technology has opened a new paradigm to controllably and reproducibly fabricate bioengineered neural constructs for potential applications in repairing …
Due to the limited regenerative ability of neural tissue, a diverse set of biochemical and biophysical cues for increasing nerve growth has been investigated, including neurotrophic …
L Huang, J Gao, H Wang, B Xia, Y Yang… - … Applied Materials & …, 2020 - ACS Publications
Biochemical and physical guidance cues are both pivotal for axonal guidance and nerve regeneration. However, fabrication of a platform that can integrate biochemical gradients …
T Fothergill, ALS Donahoo, A Douglass… - Cerebral …, 2014 - academic.oup.com
The left and right sides of the nervous system communicate via commissural axons that cross the midline during development using evolutionarily conserved molecules. These …
DJ Sutherland, Z Pujic, GJ Goodhill - Trends in neurosciences, 2014 - cell.com
Guidance of axons to their targets in the developing nervous system requires a myriad of downstream signaling molecules to coordinate growth cone movement. One of the most …