Pre-eclampsia and fetal growth restriction arise from disorders of placental development and
have some shared mechanistic features. Initiation is often rooted in the maldevelopment of a …

The placenta is essential for the efficient delivery of nutrients and oxygen from mother to
fetus to maintain normal fetal growth. Dysfunctional placental development underpins many …

Background: Perfluorooctanoic acid (PFOA) is a poly-and perfluoroalkyl substance (PFAS)
associated with adverse pregnancy outcomes in mice and humans, but little is known …

Zika virus (ZIKV) infection during pregnancy leads to an increased risk of fetal growth
restriction and fetal central nervous system malformations, which are outcomes broadly …

Plastics are ubiquitous and, when released into the environment, break down into smaller
particles termed microplastics (MPs) and nanoplastics (NPs). These MPs and NPs can be …

Pregnancy entails a large negative balance of iron, an essential micronutrient. During
pregnancy, iron requirements increase substantially to support both maternal red blood cell …

Abstract 1 in 5 women report cannabis use during pregnancy, with nausea cited as their
primary motivation. Studies show that (-)-△ 9–tetrahydrocannabinol (Δ9-THC), the major …

Fetal growth restriction (FGR) is often the result of placental insufficiency and is
characterized by insufficient transplacental transport of nutrients and oxygen. The main …

The burden of adverse pregnancy outcomes such as preterm birth and low birth weight is
considerable across the world. Several risk factors for adverse pregnancy outcomes have …

Pregnancies in women of advanced maternal age (AMA) are susceptible to fetal growth
restriction (FGR) and stillbirth. We hypothesised that maternal ageing is associated with …