Block-and-lock strategies to cure HIV infection
G Vansant, A Bruggemans, J Janssens, Z Debyser - Viruses, 2020 - mdpi.com
Today HIV infection cannot be cured due to the presence of a reservoir of latently infected
cells inducing a viral rebound upon treatment interruption. Hence, the latent reservoir is …
cells inducing a viral rebound upon treatment interruption. Hence, the latent reservoir is …
The role of immune activation and antigen persistence in acute and long COVID
S Opsteen, JK Files, T Fram… - Journal of Investigative …, 2023 - journals.sagepub.com
In late 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) triggered the
global coronavirus disease 2019 (COVID-19) pandemic. Although most infections cause a …
global coronavirus disease 2019 (COVID-19) pandemic. Although most infections cause a …
[HTML][HTML] Utilization of immunological ratios in HIV: Implications for monitoring and therapeutic strategies
Human immunodeficiency virus (HIV) infection remains a significant global health concern,
necessitating ongoing research and innovation in the quest for improved disease …
necessitating ongoing research and innovation in the quest for improved disease …
Safety and immunogenicity of the ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 in HIV infection: a single-arm substudy of a phase 2/3 clinical trial
Background Data on vaccine immunogenicity against SARS-CoV-2 are needed for the 40
million people globally living with HIV who might have less functional immunity and more …
million people globally living with HIV who might have less functional immunity and more …
Coronavirus 2019 and people living with human immunodeficiency virus: outcomes for hospitalized patients in New York City
Background There are limited data regarding the clinical impact of coronavirus disease
2019 (COVID-19) on people living with human immunodeficiency virus (PLWH). In this …
2019 (COVID-19) on people living with human immunodeficiency virus (PLWH). In this …
Humoral and cellular immune response elicited by mRNA vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in people living with …
Abstract Background Data on SARS-CoV-2 vaccine immunogenicity in PLWH are currently
limited. Aim of the study was to investigate immunogenicity according to current CD4 T-cell …
limited. Aim of the study was to investigate immunogenicity according to current CD4 T-cell …
Safety and efficacy of the mRNA BNT162b2 vaccine against SARS-CoV-2 in five groups of immunocompromised patients and healthy controls in a prospective open …
P Bergman, O Blennow, L Hansson, S Mielke… - …, 2021 - thelancet.com
Background Patients with immunocompromised disorders have mainly been excluded from
clinical trials of vaccination against COVID-19. Thus, the aim of this prospective clinical trial …
clinical trials of vaccination against COVID-19. Thus, the aim of this prospective clinical trial …
SARS-CoV-2, SARS-CoV-1, and HIV-1 derived ssRNA sequences activate the NLRP3 inflammasome in human macrophages through a non-classical pathway
GR Campbell, RK To, J Hanna, SA Spector - Iscience, 2021 - cell.com
Macrophages promote an early host response to infection by releasing pro-inflammatory
cytokines such as interleukin-1β (IL-1β), TNF, and IL-6. The bioactivity of IL-1β is classically …
cytokines such as interleukin-1β (IL-1β), TNF, and IL-6. The bioactivity of IL-1β is classically …
Gut microbiota linked to sexual preference and HIV infection
The precise effects of HIV-1 on the gut microbiome are unclear. Initial cross-sectional studies
provided contradictory associations between microbial richness and HIV serostatus and …
provided contradictory associations between microbial richness and HIV serostatus and …
[PDF][PDF] Hematologic Support in HIV Patients: Blood Transfusion Strategies and Immunological Considerations
ABSTRACT HIV infection presents multifaceted challenges, particularly in managing
hematologic complications that significantly impact patient well-being and prognosis …
hematologic complications that significantly impact patient well-being and prognosis …