Obesity and the risk of cardiometabolic diseases

PL Valenzuela, P Carrera-Bastos… - Nature reviews …, 2023 - nature.com
The prevalence of obesity has reached pandemic proportions, and now approximately 25%
of adults in Westernized countries have obesity. Recognized as a major health concern …

Association of obesity with survival outcomes in patients with cancer: a systematic review and meta-analysis

F Petrelli, A Cortellini, A Indini, G Tomasello… - JAMA Network …, 2021 - jamanetwork.com
Importance Obesity, defined as a body mass index (BMI) greater than 30, is associated with
a significant increase in the risk of many cancers and in overall mortality. However, various …

Myosteatosis in the context of skeletal muscle function deficit: an interdisciplinary workshop at the National Institute on Aging

R Correa-de-Araujo, O Addison, I Miljkovic… - Frontiers in …, 2020 - frontiersin.org
Skeletal muscle fat infiltration (known as myosteatosis) is an ectopic fat depot that increases
with aging and is recognized to negatively correlate with muscle mass, strength, and mobility …

Global patterns in excess body weight and the associated cancer burden

H Sung, RL Siegel, LA Torre… - CA: a cancer journal …, 2019 - Wiley Online Library
The prevalence of excess body weight and the associated cancer burden have been rising
over the past several decades globally. Between 1975 and 2016, the prevalence of excess …

[HTML][HTML] Sarcopenia in the older adult with cancer

GR Williams, RF Dunne, S Giri… - Journal of Clinical …, 2021 - ncbi.nlm.nih.gov
The term sarcopenia, derived from the Greek words sarx for flesh and penia for loss, was first
introduced by Rosenberg 1 in 1989 to describe the loss of muscle mass that accompanies …

Explaining the obesity paradox: the association between body composition and colorectal cancer survival (C-SCANS Study)

BJ Caan, JA Meyerhardt, CH Kroenke, S Alexeeff… - … , biomarkers & prevention, 2017 - AACR
Background: Body composition may partially explain the U-shaped association between
body mass index (BMI) and colorectal cancer survival. Methods: Muscle and adiposity at …

Obesity or BMI paradox? Beneath the tip of the iceberg

LM Donini, A Pinto, AM Giusti, A Lenzi… - Frontiers in …, 2020 - frontiersin.org
The obesity paradox refers to extant evidence showing that obesity in older subjects or in
patients with several chronic diseases may be protective and associated with decreased …

Updated prognostic factors in localized NSCLC

S Garinet, P Wang, A Mansuet-Lupo, L Fournel… - Cancers, 2022 - mdpi.com
Simple Summary In resected lung cancer, adjuvant and neoadjuvant chemotherapy
following surgery are currently mainly based on TNM classification. With the validation and …

[HTML][HTML] Contribution of adipose tissue to development of cancer

AJ Cozzo, AM Fuller, L Makowski - Comprehensive Physiology, 2017 - ncbi.nlm.nih.gov
Solid tumor growth and metastasis require the interaction of tumor cells with the surrounding
tissue, leading to a view of tumors as tissue-level phenomena rather than exclusively cell …

Obesity paradox and aging

O Bosello, A Vanzo - Eating and Weight Disorders-Studies on Anorexia …, 2021 - Springer
Background In association with the rapid lengthening of life expectancy and the ever-rising
prevalence of obesity, many studies explored in the elderly the phenomenon usually defined …