Therapeutic strategies for hepatitis B virus infection: towards a cure

GC Fanning, F Zoulim, J Hou, A Bertoletti - Nature reviews Drug …, 2019 - nature.com
Chronic hepatitis B virus (HBV) infection is a common cause of liver disease globally, with a
disproportionately high burden in South-East Asia. Vaccines and nucleoside or nucleotide …

Roadmap to functional cure of chronic hepatitis B: an expert consensus

Q Ning, DI Wu, GQ Wang, H Ren, ZL Gao… - Journal of viral …, 2019 - Wiley Online Library
Hepatitis B virus (HBV) infection continues to be a major public health issue worldwide.
HBsAg loss is associated with functional remission and improved long‐term outcome, and is …

Chronic hepatitis B: the demise of the 'inactive carrier'phase

A Koffas, M Kumar, US Gill, A Jindal… - Hepatology …, 2021 - Springer
Chronic hepatitis B (CHB) remains a global healthcare burden. Although the recent
developments in the field have led to a reduction in incidence, the morbidity and mortality …

Reasons to consider early treatment in chronic hepatitis B patients

A Koffas, J Petersen, PT Kennedy - Antiviral research, 2020 - Elsevier
In spite of a decrease in the prevalence and incidence seen in recent years, chronic
hepatitis B (CHB) still remains a major healthcare challenge, prevalent mostly in developing …

Current treatment of chronic hepatitis B: Clinical aspects and future directions

M Zhu, H Wang, T Lou, P Xiong, J Zhang, L Li… - Frontiers in …, 2022 - frontiersin.org
Hepatitis B virus (HBV) infection is a public health threat worldwide, and there is no direct
treatment yet available. In the event of infection, patients may present liver cirrhosis and …

Hepatitis B Therapeutic Vaccine: A Patent Review

SA Hudu, AO Jimoh, KG Ibrahim, AS Alshrari - Pharmaceuticals, 2022 - mdpi.com
Viral hepatitis has long been underrated as a danger to global health. The UN only recently
called for worldwide action to tackle viral hepatitis and lessen the disease burden in its …

Early treatment consideration in patients with hepatitis B 'e'antigen-positive chronic infection: Is it time for a paradigm shift?

A Koffas, LY Mak, US Gill, PTF Kennedy - Viruses, 2022 - mdpi.com
Chronic hepatitis B (CHB) is associated with significant morbidity and mortality, due to the
adverse sequelae of cirrhosis and hepatocellular carcinoma (HCC). To date, antiviral …

[HTML][HTML] Diffusion-weighted magnetic resonance imaging and micro-RNA in the diagnosis of hepatic fibrosis in chronic hepatitis C virus

T Besheer, H Elalfy, M Abd El-Maksoud… - World Journal of …, 2019 - ncbi.nlm.nih.gov
BACKGROUND Diffusion-weighted magnetic resonance imaging has shown promise in the
detection and quantification of hepatic fibrosis. In addition, the liver has numerous …

Chronic Hepatitis B: Treat all Who Are Viremic?

F Su, IM Jacobson - Clinics in Liver Disease, 2023 - liver.theclinics.com
The goals of antiviral therapy in patients with chronic hepatitis B (CHB) are to prevent
disease progression and reduce the risk of hepatocellular carcinoma (HCC). 1–3 Treatment …

Clinical performance of Determine HBsAg 2 rapid test for Hepatitis B detection

A Avellon, A Ala, A Diaz, D Domingo… - Journal of Medical …, 2020 - Wiley Online Library
Hepatitis B virus (HBV) infection is estimated to affect 292 million people worldwide, 90% of
them are unaware of their HBV status. The Determine HBsAg 2 (Alere Medical Co, Ltd Chiba …