An equilibrium needs to be established by the cellular and acellular components of the
ovarian follicle if developmental competence is to be acquired by the oocyte. Both cumulus …

Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility;
however, whether women with PCOS and spontaneous or drug-induced ovulatory cycles …

The female ovary contains a finite number of oocytes, and their release at ovulation
becomes sporadic and disordered with aging and with obesity, leading to loss of fertility …

Inflammation is a biologic process that mediates tissue effects including vasodilation,
hyperemia, edema, collagenolysis, and cell proliferation through complex immunologic …

Premature ovarian insufficiency (POI) is a condition that arises from dysfunction or early
depletion of the ovarian follicle pool accompanied by an earlier-than-normal loss of fertility in …

Disclosures: This work was supported by grant K12HD063086 from the National Institutes of
Health (NIH), Bethesda, Maryland. The contents of this work are the responsibility of the …

Increasing evidence on the significance of nutrition in reproduction is emerging from both
animal and human studies, suggesting a mutual association between nutrition and female …

Female aging is one of the most important factors that impacts human reproduction. With
aging, there is a natural decline in female fertility. The decrease in fertility is slow and steady …

Metabolic conditions characterized by elevated free fatty acid concentrations in blood and
follicular fluid are often associated with impaired female fertility. Especially elevated …

Context: Variability in the pattern of change in estradiol (E2) and FSH levels over the
menopause transition has not been well defined. Objective: The current study aimed to …