Recent progress in the science of complex coacervation

CE Sing, SL Perry - Soft Matter, 2020 - pubs.rsc.org
Complex coacervation is an associative, liquid–liquid phase separation that can occur in
solutions of oppositely-charged macromolecular species, such as proteins, polymers, and …

Intrinsically disordered protein regions and phase separation: sequence determinants of assembly or lack thereof.

EW Martin, AS Holehouse - Emerging topics in life sciences, 2020 - europepmc.org
Intrinsically disordered protein regions (IDRs)-regions that do not fold into a fixed three-
dimensional structure but instead exist in a heterogeneous ensemble of conformations-have …

Driving force and pathway in polyelectrolyte complex coacervation

S Chen, ZG Wang - … of the National Academy of Sciences, 2022 - National Acad Sciences
There is notable discrepancy between experiments and coarse-grained model studies
regarding the thermodynamic driving force in polyelectrolyte complex coacervation …

Development of the modern theory of polymeric complex coacervation

CE Sing - Advances in colloid and interface science, 2017 - Elsevier
Oppositely charged polymers can undergo the process of complex coacervation, which
refers to a liquid–liquid phase separation driven by electrostatic attraction. These materials …

Complex coacervation of proteins and anionic polysaccharides

CG De Kruif, F Weinbreck, R de Vries - Current opinion in colloid & …, 2004 - Elsevier
Coacervation of proteins and anionic polysaccharides is both of practical and theoretical
interest. From a large body of literature, it seems that the phase separation is mainly …

Structure and technofunctional properties of protein-polysaccharide complexes: a review

C Schmitt, C Sanchez, S Desobry-Banon… - Critical reviews in food …, 1998 - Taylor & Francis
Food proteins and polysaccharides are the two key structural entities in food materials.
Generally, interactions between proteins and polysaccharides in aqueous media can lead to …

Driving forces of the complex formation between highly charged disordered proteins

A Chowdhury, A Borgia, S Ghosh… - Proceedings of the …, 2023 - National Acad Sciences
Highly disordered complexes between oppositely charged intrinsically disordered proteins
present a new paradigm of biomolecular interactions. Here, we investigate the driving forces …

Binodal compositions of polyelectrolyte complexes

E Spruijt, AH Westphal, JW Borst… - …, 2010 - ACS Publications
When oppositely charged polyelectrolytes are mixed below a critical salt concentration, their
mixtures show macroscopic phase separation into a dilute and a dense, polyelectrolyte …

The effect of salt on the complex coacervation of vinyl polyelectrolytes

SL Perry, Y Li, D Priftis, L Leon, M Tirrell - Polymers, 2014 - mdpi.com
Complex coacervation is an electrostatically-driven phase separation phenomenon that is
utilized in a wide range of everyday applications and is of great interest for the creation of …

Thermodynamic characterization of polypeptide complex coacervation

D Priftis, N Laugel, M Tirrell - Langmuir, 2012 - ACS Publications
The interactions between a series of oppositely charged polypeptide pairs are probed using
isothermal titration calorimetry (ITC) in combination with turbidity measurements and optical …