The life and times of a tRNA
EM Phizicky, AK Hopper - RNA, 2023 - rnajournal.cshlp.org
The study of eukaryotic tRNA processing has given rise to an explosion of new information
and insights in the last several years. We now have unprecedented knowledge of each step …
and insights in the last several years. We now have unprecedented knowledge of each step …
Colicin biology
E Cascales, SK Buchanan, D Duché… - Microbiology and …, 2007 - Am Soc Microbiol
Colicins are proteins produced by and toxic for some strains of Escherichia coli. They are
produced by strains of E. coli carrying a colicinogenic plasmid that bears the genetic …
produced by strains of E. coli carrying a colicinogenic plasmid that bears the genetic …
tRNA-derived fragments (tRFs): emerging new roles for an ancient RNA in the regulation of gene expression
SP Keam, G Hutvagner - Life, 2015 - mdpi.com
This review will summarise the recent discoveries and current state of research on short
noncoding RNAs derived from tRNAs—known as tRNA-derived fragments (tRFs). It will …
noncoding RNAs derived from tRNAs—known as tRNA-derived fragments (tRFs). It will …
tRNA cleavage is a conserved response to oxidative stress in eukaryotes
Recent results have identified a diversity of small RNAs in a wide range of organisms. In this
work, we demonstrate that Saccharomyces cerevisiae contains a small RNA population …
work, we demonstrate that Saccharomyces cerevisiae contains a small RNA population …
[HTML][HTML] The bacterial toxin RelE displays codon-specific cleavage of mRNAs in the ribosomal A site
K Pedersen, AV Zavialov, MY Pavlov, J Elf, K Gerdes… - Cell, 2003 - cell.com
The Escherichia coli relBE operon encodes a toxin-antitoxin pair, RelE-RelB. RelB can
reverse inhibition of protein synthesis by RelE in vivo. We have found that although RelE …
reverse inhibition of protein synthesis by RelE in vivo. We have found that although RelE …
Angiogenin generates specific stress-induced tRNA halves and is not involved in tRF-3–mediated gene silencing
tRNA fragments (tRFs) and tRNA halves have been implicated in various cellular processes,
including gene silencing, translation, stress granule assembly, cell differentiation …
including gene silencing, translation, stress granule assembly, cell differentiation …
The role of RNA modifications in the regulation of tRNA cleavage
Transfer RNA (tRNA) have been harbingers of many paradigms in RNA biology. They are
among the first recognized noncoding RNA (ncRNA) playing fundamental roles in RNA …
among the first recognized noncoding RNA (ncRNA) playing fundamental roles in RNA …
Mechanism and biological role of Dnmt2 in nucleic acid methylation
A Jeltsch, A Ehrenhofer-Murray, TP Jurkowski… - RNA biology, 2017 - Taylor & Francis
ABSTRACT A group of homologous nucleic acid modification enzymes called Dnmt2,
Trdmt1, Pmt1, DnmA, and Ehmet in different model organisms catalyze the transfer of a …
Trdmt1, Pmt1, DnmA, and Ehmet in different model organisms catalyze the transfer of a …
Enteric virulence associated protein VapC inhibits translation by cleavage of initiator tRNA
KS Winther, K Gerdes - Proceedings of the National …, 2011 - National Acad Sciences
Eukaryotic PIN (PilT N-terminal) domain proteins are ribonucleases involved in quality
control, metabolism and maturation of mRNA and rRNA. The majority of prokaryotic PIN …
control, metabolism and maturation of mRNA and rRNA. The majority of prokaryotic PIN …
tRNA-derived small RNAs: biogenesis, modification, function and potential impact on human disease development
V Oberbauer, MR Schaefer - Genes, 2018 - mdpi.com
Transfer RNAs (tRNAs) are abundant small non-coding RNAs that are crucially important for
decoding genetic information. Besides fulfilling canonical roles as adaptor molecules during …
decoding genetic information. Besides fulfilling canonical roles as adaptor molecules during …