Although theory suggests individuals are more willing to incur a personal cost to benefit
ingroup members, compared to outgroup members, there is inconsistent evidence in support …

It has been known for many years that the mutation rate varies across the genome. However,
only with the advent of large genomic data sets is the full extent of this variation becoming …

We present a DNA library preparation method that has allowed us to reconstruct a high-
coverage (30×) genome sequence of a Denisovan, an extinct relative of Neandertals. The …

Apes possess two sex chromosomes—the male-specific Y chromosome and the X
chromosome, which is present in both males and females. The Y chromosome is crucial for …

Meiotic recombination and de novo mutation are the two main contributions toward gamete
genome diversity, and many questions remain about how an individual human's genome is …

Although mutation provides the fuel for phenotypic evolution, it also imposes a substantial
burden on fitness through the production of predominantly deleterious alleles, a matter of …

Here we present a draft genome sequence of the common chimpanzee (Pan troglodytes).
Through comparison with the human genome, we have generated a largely complete …

Because germline mutations are the source of all evolutionary adaptations and heritable
diseases, characterizing their properties and the rate at which they arise across individuals …

The textbook view that most germline mutations in mammals arise from replication errors is
indirectly supported by the fact that there are both more mutations and more cell divisions in …

Recombination is typically thought of as a symmetrical process resulting in large-scale
reciprocal genetic exchanges between homologous chromosomes. Recombination events …