Background. In an attempt to decrease the toxic effects of fluorouracil, doxorubicin, and
methotrexate (FAMTX) by reducing the dose of methotrexate from 1500 mg/m2, according to …

Thirty-four patients with locally advanced, nonresectable gastric cancer (staged by
laparotomy) received etoposide, Adriamycin (doxorubicin; Adria Laboratories, Columbus …

In this phase II multicenter trial, 67 evaluable patients with advanced measurable gastric
carcinoma were treated with a combination of etoposide, Adriamycin (doxorubicin; Adria …

While in the US, the annual incidence of gastric cancer has been steadily declining from 28
per 100,000 in 1930 to less than 10 in the 80's, it remains a very frequent tumor in Japan …

The chemotherapy of gastric carcinoma is at an important point in its evolution. Multiple
studies with a variety of agents have demonstrated that combination chemotherapy appears …

PEGylated liposomes have transformed chemotherapeutic use of doxorubicin by reducing
its cardiotoxicity; however, it remains unclear whether liposomal doxorubicin is …

Background Intestinal injury is one of the main side-effects of cisplatin chemotherapy,
impairing the quality of life in patients with cancer. In this study, we investigated the …

Around 12,000 people each year in the United Kingdom develop gastric adenocarcinoma
(Office of Population Censuses & Surveys, 1986). For the majority of patients, the diagnosis …

A review of the present status of adjuvant chemotherapy for gastric cancer in Japan has
been made. The single use of mitomycin C (MMC) after curative gastrectomy, a multidrug …

Despite a steady decline in incidence over the past five decades in this country, gastric
carcinoma continues to represent a major health problem. From the turn of the century …