Role of PI3K-AKT pathway in ultraviolet ray and hydrogen peroxide-induced oxidative damage and its repair by grain ferments

W Cheng, X Shi, J Zhang, L Li, F Di, M Li, C Wang… - Foods, 2023 - mdpi.com
UV and external environmental stimuli can cause oxidative damage to skin cells. However,
the molecular mechanisms involved in cell damage have not been systematically and …

Karanjin: a potential furanoflavonoid for neuroprotection

C Gnanaraj, M Govendan, CY Loo, YS Yong… - Phytochemistry …, 2024 - Springer
Phytochemicals are widely known for the pharmacological effects in treating various human
conditions and in recent years, new compounds are being discovered with substantial …

Valorization of Pongame Oiltree (Millettia pinnata) Seed and Seed Oil: A Promising Source of Phytochemicals and Its Applications

TB Devidas, A Vyas, K Sridhar, P Chawla… - Waste and Biomass …, 2023 - Springer
Pongame oiltree (Millettia pinnata) is one of the medicinal plants that are grown in humid
subtropical climate zones. The seeds are the major source of furanoflavonoids karanjin and …

Phytochemicals: a Natural Prospect Toward Healthcare—a Tryst with Karanjin

G Bhatt, AM Limaye, L Rangan - Proceedings of the National Academy of …, 2024 - Springer
The majority of the world's population still relies on plant-based products as therapeutic
agents to enhance health. Flavonoids are an important class of phytochemicals and possess …

The cytotoxicity of karanjin toward breast cancer cells is involved in the PI3K/Akt signaling pathway

J Yu, H Yang, C Lv, X Dai - Drug Development Research, 2022 - Wiley Online Library
Karanjin is a bioactive furanoflavonoid with various pharmacological activities including
anticancer activities. However, the effect and the related mechanism of karanjin in breast …

Comparative Computational Screening of Natural-based Partial Agonists for PPARγ Receptor

L Moradihaghgou, R Schneider, BM Zanjani… - Medicinal …, 2023 - ingentaconnect.com
Introduction: The nuclear transcription factor PPARγ, which can modulate cell growth via
proliferation and apoptosis-related mechanisms, is a promising target in cancer therapy …