Glycosaminoglycans (GAGs) and proteoglycans (PGs) are essential components of the
extracellular matrix (ECM) with pivotal roles in cellular mechanosensing pathways. GAGs …

The tumor microenvironment (TME), which includes both cellular and non-cellular elements,
is now recognized as one of the major regulators of the development of primary tumors, the …

Hyaluronic acid (HA) is widely distributed in human connective tissue, and its unique
biological and physicochemical properties and ability to facilitate biological structure repair …

Stress profoundly affects physical and mental health, particularly when experienced early in
life. Early-life stress (ELS) encompasses adverse childhood experiences such as abuse …

With the application of high throughput sequencing technologies at single-cell resolution,
studies of the tumor microenvironment in glioblastoma, one of the most aggressive and …

Tumors are a heterogeneous group of cell masses originating in various organs or tissues.
The cellular composition of the tumor cell mass interacts in an intricate manner, influenced …

Glioblastoma multiform (GBM) tumor progression has been recognized to be correlated with
extracellular matrix (ECM) stiffness. Dynamic variation of tumor ECM is primarily regulated …

The resistance of glioblastomas (GBM) to standard therapies poses a clinical challenge with
limited survival despite interventions. The tumor microenvironment (TME) orchestrates GBM …

Surgical resection is a mainstay of treatment for many tumors in addition to radiation and
systemic therapy. Often, the margin between normal and neoplastic tissue is difficult for …

Triple‐negative breast cancer (TNBC) is the most invasive type of breast cancer with high
risk of brain metastasis. To better understand interactions between breast tumors with the …