Dietary sources, health benefits, and risks of caffeine

A Saimaiti, DD Zhou, J Li, RG Xiong… - Critical Reviews in …, 2023 - Taylor & Francis
Dietary intake of caffeine has significantly increased in recent years, and beneficial and
harmful effects of caffeine have been extensively studied. This paper reviews antioxidant …

The putative role of neuroinflammation in the interaction between traumatic brain injuries, sleep, pain and other neuropsychiatric outcomes: a state-of-the-art review

A Herrero Babiloni, AA Baril… - Journal of clinical …, 2023 - mdpi.com
Sleep disturbances are widely prevalent following a traumatic brain injury (TBI) and have the
potential to contribute to numerous post-traumatic physiological, psychological, and …

Stress-induced microglial activation occurs through β-adrenergic receptor: noradrenaline as a key neurotransmitter in microglial activation

S Sugama, T Takenouchi, M Hashimoto… - Journal of …, 2019 - Springer
Background The involvement of microglia in neuroinflammatory responses has been
extensively demonstrated. Recent animal studies have shown that exposure to either acute …

[HTML][HTML] TNF signaling pathway-mediated microglial activation in the PFC underlies acute paradoxical sleep deprivation-induced anxiety-like behaviors in mice

H Liu, X Huang, Y Li, K Xi, Y Han, H Mao, K Ren… - Brain, behavior, and …, 2022 - Elsevier
Acute sleep deprivation is a common condition in modern life and increases anxiety
symptoms in healthy individuals. The neuroinflammatory response induced by microglial …

Overview of caffeine effects on human health and emerging delivery strategies

SM Saraiva, TA Jacinto, AC Gonçalves, D Gaspar… - Pharmaceuticals, 2023 - mdpi.com
Caffeine is a naturally occurring alkaloid found in various plants. It acts as a stimulant,
antioxidant, anti-inflammatory, and even an aid in pain management, and is found in several …

Hydrogen sulfide antagonizes sleep deprivation-induced depression-and anxiety-like behaviors by inhibiting neuroinflammation in a hippocampal Sirt1-dependent …

X Kang, L Jiang, F Lan, YY Tang, P Zhang, W Zou… - Brain Research …, 2021 - Elsevier
Increasing evidence confirms that sleep deprivation (SD), which induces hippocampal
neuroinflammation, is a risk factor for depression. Hydrogen sulfide (H 2 S) is a novel …

Microglia dynamics in sleep/wake states and in response to sleep loss

S Deurveilher, T Golovin, S Hall, K Semba - Neurochemistry International, 2021 - Elsevier
Sleep has an essential role for optimal brain function, but the cellular substrates for sleep
regulation are not fully understood. Microglia, the immune cells of the brain, have gained …

Differentially expressed genes in the brain of aging mice with cognitive alteration and depression-and anxiety-like behaviors

M Li, S Su, W Cai, J Cao, X Miao, W Zang… - Frontiers in Cell and …, 2020 - frontiersin.org
Despite the great increase in human lifespan with improved medical care, the physiological
and pathological changes such as memory and cognitive disorders and associated anxiety …

Role of astrocytes in sleep deprivation: accomplices, resisters, or bystanders?

M Que, Y Li, X Wang, G Zhan, X Luo… - Frontiers in Cellular …, 2023 - frontiersin.org
Sleep plays an essential role in all studied animals with a nervous system. However, sleep
deprivation leads to various pathological changes and neurobehavioral problems …

Complement activation sustains neuroinflammation and deteriorates adult neurogenesis and spatial memory impairment in rat hippocampus following sleep …

M Wadhwa, A Prabhakar, JP Anand, K Ray… - Brain, Behavior, and …, 2019 - Elsevier
Background An association between neuroinflammation, reduced adult neurogenesis, and
cognitive impairment has been established in sleep deprivation (SD). Complement …