Urinary MicroRNAs as biomarkers of urological cancers: a systematic review

A Aveta, S Cilio, R Contieri, G Spena… - International Journal of …, 2023 - mdpi.com
MicroRNAs (miRNAs) are emerging as biomarkers for the detection and prognosis of
cancers due to their inherent stability and resilience. To summarize the evidence regarding …

MicroRNAs in human cancer

TA Farazi, JI Hoell, P Morozov, T Tuschl - MicroRNA cancer regulation …, 2013 - Springer
Mature microRNAs (miRNAs) are single-stranded RNA molecules of 20–23-nucleotide (nt)
length that control gene expression in many cellular processes. These molecules typically …

PSA and beyond: alternative prostate cancer biomarkers

S Saini - Cellular Oncology, 2016 - Springer
Background The use of biomarkers for prostate cancer screening, diagnosis and prognosis
has the potential to improve the clinical management of the patients. Owing to inherent …

Targeting pyruvate dehydrogenase kinase signaling in the development of effective cancer therapy

S Anwar, A Shamsi, T Mohammad, A Islam… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Pyruvate is irreversibly decarboxylated to acetyl coenzyme A by mitochondrial pyruvate
dehydrogenase complex (PDC). Decarboxylation of pyruvate is considered a crucial step in …

The potential of microRNAs as prostate cancer biomarkers

L Fabris, Y Ceder, AM Chinnaiyan, GW Jenster… - European urology, 2016 - Elsevier
Abstract Context Short noncoding RNAs known as microRNAs (miRNAs) control protein
expression through the degradation of RNA or the inhibition of protein translation. The …

miRNAs in human cancer

TA Farazi, JI Spitzer, P Morozov… - The Journal of …, 2011 - Wiley Online Library
Mature microRNAs (miRNAs) are single‐stranded RNA molecules of 20–23 nucleotide (nt)
length that control gene expression in many cellular processes. These molecules typically …

The dual role of TGFβ in human cancer: from tumor suppression to cancer metastasis

JJ Lebrun - International Scholarly Research Notices, 2012 - Wiley Online Library
The transforming growth factor‐beta (TGFβ) superfamily encompasses widespread and
evolutionarily conserved polypeptide growth factors that regulate and orchestrate growth …

Plasma extracellular RNA profiles in healthy and cancer patients

T Yuan, X Huang, M Woodcock, M Du, R Dittmar… - Scientific reports, 2016 - nature.com
Extracellular vesicles are selectively enriched in RNA that has potential as disease
biomarkers. To systemically characterize circulating extracellular RNA (exRNA) profiles, we …

MicroRNA-181b regulates NF-κB–mediated vascular inflammation

X Sun, B Icli, AK Wara, N Belkin, S He… - The Journal of …, 2012 - Am Soc Clin Investig
EC activation and dysfunction have been linked to a variety of vascular inflammatory
disease states. The function of microRNAs (miRNAs) in vascular EC activation and …

Circulating miRNAs are correlated with tumor progression in prostate cancer

JC Brase, M Johannes, T Schlomm… - … journal of cancer, 2011 - Wiley Online Library
Circulating miRNAs have recently been indicated as practicable and promising biomarkers
for noninvasive diagnosis in various tumor entities. However, cell‐free miRNAs have not …