Traditional therapeutic approaches such as chemotherapy and radiation therapy have
burdened cancer patients with onerous physical and psychological challenges …

Cancer presents a formidable threat to human health, with the majority of cases currently
lacking a complete cure. Frequently, chemotherapy drugs are required to impede its …

Ferroptosis is a non-apoptotic cell death pathway characterized by the accumulation of lipid-
peroxy radicals within the affected cells. Here, we investigate the synergistic capacity of …

Biomedical polymers play a key role in preventing, diagnosing, and treating diseases,
showcasing a wide range of applications. Their unique advantages, such as rich source …

Even though chemotherapy stands as a standard option in the therapy of TNBC, problems
associated with it such as anemia, bone marrow suppression, immune suppression, toxic …

Mathematical models are used to characterize and optimize drug release in drug delivery
systems (DDS). One of the most widely used DDS is the poly (lactic-co-glycolic acid)(PLGA) …

Certain aggressive cancers, such as triple-negative breast cancer (TNBC), heavily bank on
glutamine for their proliferation and survival. In this context, TNBC functions as a “glutamine …

Ferroptosis, a pathway dependent on oxygen and iron catalysts, holds promise as a
therapeutic approach for cancer treatment due to its manageable regulation, direct control …

Triple-negative breast cancer (TNBC) is a highly aggressive subtype of breast cancer that
lacks expression of estrogen, progesterone, and HER2 receptor targets for therapy …

In this study, we investigated the potential of the sorafenib (SOR) and simvastatin (SIM)
combination to induce ferroptosis-mediated cancer therapy. To enhance targeted drug …