Over the past decade, the global scientific community have begun to recognize the
unmatched value of an extraordinary drug, ivermectin, that originates from a single microbe …

The most commonly used modern anthelmintics include the benzimidazoles, the nicotinic
agonists, praziquantel, triclabendazole and the macrocyclic lactones. These drugs interfere …

Background The near exclusive use of praziquantel (PZQ) for treatment of human
schistosomiasis has raised concerns about the possible emergence of drug-resistant …

Praziquantel is the drug of choice for the treatment of all forms of schistosomiasis. This
review summarizes the main features of the drug, with special attention being given to those …

Schistosomiasis is the second most important human parasitic disease in terms of
socioeconomic impact, causing great morbidity and mortality, predominantly across the …

In this review the available reports on drug resistance in human helminths, particularly
hookworms and schistosomes, are critically analyzed. The experiences with helminths of …

The efficacy of praziquantel against a Puerto Rican strain of Schistosoma mansoni was
assessed using both in vivo and in vitro approach. The drug effective dose (50%) in the …

Schistosomiasis remains one of the most prevalent parasitic diseases in developing
countries. After malaria, schistosomiasis is the most important tropical disease in terms of …

Tropical diseases remain severe threats to global health with acute or chronic debility.
Public health issues are regularly monitored and reported by the WHO. Conditions with high …

Background Schistosomiasis is a chronic, debilitating parasitic disease infecting more than
200 million people and is second only to malaria in terms of public health importance. Due …