Conspectus Fluorescent labels and biosensors play central roles in biological and medical
research. Targeted to specific biomolecules or cells, they allow noninvasive imaging of the …

Mitochondria are dynamic organelles that integrate bioenergetics, biosynthesis, and
signaling in cells and regulate redox homeostasis, apoptotic pathways, and cell proliferation …

Biocompatible fluorescent reporters with spectral properties spanning the entire visible
spectrum are indispensable tools for imaging the biochemistry of living cells and organisms …

Far‐red emitting fluorescent labels are highly desirable for spectral multiplexing and deep
tissue imaging. Here, we describe the generation of frFAST (far‐red Fluorescence Activating …

Our ability to observe biochemical events with high spatial and temporal resolution is
essential for understanding the functioning of living systems. Intrinsically fluorescent proteins …

We present a comprehensive review of super-resolution optical fluctuation imaging (SOFI), a
robust technique that leverages temporal fluctuations in fluorescence intensity to achieve …

Super resolution microscopy methods have been designed to overcome the physical barrier
of the diffraction limit and push the resolution to nanometric scales. A recently developed …

Abstract Synapse associated protein-97/Human Disk Large (SAP97/hDLG) is a conserved,
alternatively spliced, modular, scaffolding protein critical in regulating the molecular …

Recently, the localization of amyloid precursor protein (APP) into reversible nanoscale
supramolecular assembly or “nanodomains” has been highlighted as crucial towards …

Despite an intuitive understanding of the role of APP in health and disease, there exist few
attempts to dissect its molecular localization at excitatory synapses. Though the biochemistry …