Macrophages represent heterogeneous cell population with important roles in defence
mechanisms and in homoeostasis. Tissue macrophages from diverse anatomical locations …

Organ transplantation remains the most optimal strategy for patients with end-stage organ
failure. However, prevailing methods of immunosuppression are marred by adverse side …

The transcriptional and phenotypic characteristics that define alveolar monocyte and
macrophage subsets in acute hypoxemic respiratory failure (AHRF) are poorly understood …

Background Surveillance bronchoscopies with bronchoalveolar lavage (BAL) and
transbronchial biopsies (TBB) are primarily used to detect acute cellular rejection (ACR) or …

Background Intrauterine adhesion (IUA) is a common cause of clinically refractory infertility,
and there exists significant heterogeneity in the treatment outcomes among IUA patients with …

A major cause of death for lung transplant recipients (LTRs) is the advent of chronic lung
allograft dysfunction (CLAD), which has long plagued the long-term post-transplant …

Abstract Background Triggering Receptor Expressed on Myeloid cells-1 (TREM-1) plays an
important role in innate immune system. However, whether and how TREM-1 contributes to …

Lung transplantation is a life-saving therapy for end-stage pulmonary disease, but its long-
term outlook is poor due to a high incidence of chronic lung allograft dysfunction (CLAD) …

Macrophages contribute to post-transplant lung rejection. Disulfiram (DSF), an antialcoholic
drug, has an anti-inflammatory effect and regulates macrophage chemotactic activity. Here …

Background Acute lung allograft dysfunction (ALAD) is an imprecise syndrome denoting
concern for the onset of chronic lung allograft dysfunction (CLAD). Mechanistic biomarkers …