Biodegradable polymers for biomedical additive manufacturing

D Puppi, F Chiellini - Applied materials today, 2020 - Elsevier
The tremendous interest received by additive manufacturing (AM) within the biomedical
community is a consequence of the great versatility offered in terms of processing approach …

Wet‐spinning of biomedical polymers: from single‐fibre production to additive manufacturing of three‐dimensional scaffolds

D Puppi, F Chiellini - Polymer International, 2017 - Wiley Online Library
Wet‐spinning of polymeric materials has been widely investigated for various biomedical
applications, such as extracorporeal blood treatment, controlled drug release and tissue …

A Novel Scaffold-Based Hybrid Multicellular Model for Pancreatic Ductal Adenocarcinoma—Toward a Better Mimicry of the in vivo Tumor Microenvironment

P Gupta, PA Pérez-Mancera, H Kocher… - … in Bioengineering and …, 2020 - frontiersin.org
With a very low survival rate, pancreatic ductal adenocarcinoma (PDAC) is a deadly
disease. This has been primarily attributed to (i) its late diagnosis and (ii) its high resistance …

The revolutionary roads to study cell–cell interactions in 3d in vitro pancreatic cancer models

D Delle Cave, R Rizzo, B Sainz Jr, G Gigli… - Cancers, 2021 - mdpi.com
Simple Summary Pancreatic cancer is an extremely lethal malignancy with a survival rate
lower than any other cancer type. For decades, two-dimensional (2D) cultures have been …

Polymeric hydrogels for in vitro 3D ovarian cancer modeling

S Braccini, C Tacchini, F Chiellini, D Puppi - International Journal of …, 2022 - mdpi.com
Ovarian cancer (OC) grows and interacts constantly with a complex microenvironment, in
which immune cells, fibroblasts, blood vessels, signal molecules and the extracellular matrix …

Jellyfish polysaccharides for wound healing applications

C Migone, N Scacciati, B Grassiri, M De Leo… - International Journal of …, 2022 - mdpi.com
Jellyfishes are considered a new potential resource in food, pharmaceutical and biomedical
industries. In these latter cases, they are studied as source of active principles but are also …

Application of hydrogels as carrier in tumor therapy: A review

Z Zhang, J Wang, W Xia, D Cao, X Wang… - Chemistry–An Asian …, 2022 - Wiley Online Library
Cancer is one of the most intractable diseases in the world because of its high recurrence
rate, high metastasis rate and high lethality rate. Traditional chemotherapy, radiotherapy and …

On the evaluation of a novel hypoxic 3D pancreatic cancer model as a tool for radiotherapy treatment screening

G Wishart, P Gupta, A Nisbet, G Schettino, E Velliou - Cancers, 2021 - mdpi.com
Simple Summary Pancreatic cancer challenges global health with non-specific symptoms,
devastatingly low survival rates, and high treatment resistance profiles. Tissue engineering …

3d tissue models as tools for radiotherapy screening for pancreatic cancer

G Wishart, P Gupta, G Schettino… - The British Journal of …, 2021 - academic.oup.com
The efficiency of radiotherapy treatment regimes varies from tumour to tumour and from
patient to patient but it is generally highly influenced by the tumour microenvironment (TME) …

Tissue-engineered 3D models for elucidating primary and metastatic bone cancer progression

ECG Diaz, S Sinha, RS Avedian, F Yang - Acta biomaterialia, 2019 - Elsevier
Malignant bone tumors are aggressive neoplasms which arise from bone tissue or as a
result of metastasis. The most prevalent types of cancer, such as breast, prostate, and lung …