Structure and function of haemoglobins

DA Gell - Blood Cells, Molecules, and Diseases, 2018 - Elsevier
Haemoglobin (Hb) is widely known as the iron-containing protein in blood that is essential
for O 2 transport in mammals. Less widely recognised is that erythrocyte Hb belongs to a …

Imidazoles as promising scaffolds for antibacterial activity: a review

N Rani, A Sharma, R Singh - Mini reviews in medicinal …, 2013 - ingentaconnect.com
In the last few decades, a lot of work has been done on heterocycles, especially the
imidazole ring, to obtain a scaffold with potential pharmacological properties such as …

Pseudomonas syringae pv. actinidiae Draft Genomes Comparison Reveal Strain-Specific Features Involved in Adaptation and Virulence to Actinidia Species

S Marcelletti, P Ferrante, M Petriccione, G Firrao… - PloS one, 2011 - journals.plos.org
A recent re-emerging bacterial canker disease incited by Pseudomonas syringae pv.
actinidiae (Psa) is causing severe economic losses to Actinidia chinensis and A. deliciosa …

Immunopharmacology of modern antifungals

RB Ami, RE Lewis… - Clinical infectious …, 2008 - academic.oup.com
In addition to their in vitro inhibitory and fungicidal effects, modern antifungal agents interact
in vivo with host immune functions involved in defense against fungal pathogens. The nature …

NO Dioxygenase Activity in Hemoglobins Is Ubiquitous In Vitro, but Limited by Reduction In Vivo

BJ Smagghe, JT Trent III, MS Hargrove - PloS one, 2008 - journals.plos.org
Genomics has produced hundreds of new hemoglobin sequences with examples in nearly
every living organism. Structural and biochemical characterizations of many recombinant …

Design, synthesis, characterizing and DFT calculations of a binary CT complex co-crystal of bioactive moieties in different polar solvents to investigate its …

M Islam, IM Khan, S Shakya, N Alam - Journal of Biomolecular …, 2023 - Taylor & Francis
Imidazole (IM) and salicylic acid (SA) have a significant class among the medical compound.
These are widely used as topical drugs like antifungal, antibacterial, anticancer …

Protection from nitrosative stress: a central role for microbial flavohemoglobin

MT Forrester, MW Foster - Free Radical Biology and Medicine, 2012 - Elsevier
Nitric oxide (NO) is an inevitable product of life in an oxygen-and nitrogen-rich environment.
This reactive diatomic molecule exhibits microbial cytotoxicity, in large part by facilitating …

Comparative Genome Analysis Provides Insights into the Evolution and Adaptation of Pseudomonas syringae pv. aesculi on Aesculus hippocastanum

S Green, DJ Studholme, BE Laue, F Dorati, H Lovell… - PLoS …, 2010 - journals.plos.org
A recently emerging bleeding canker disease, caused by Pseudomonas syringae pathovar
aesculi (Pae), is threatening European horse chestnut in northwest Europe. Very little is …

Synthesis and characterization of a novel Mannich base benzimidazole derivative to explore interaction with human serum albumin and antimicrobial property …

FM Mashood Ahamed, B Shakya… - Journal of Biomolecular …, 2023 - Taylor & Francis
The novel Mannich base benzimidazole derivative (CB-1), 1-((1H-benzo [d] imidazol-1-yl)(3-
chlorophenyl) methyl)-3-phenylurea) has been designed and synthesized by reacting …

Imidazole derivatives and their antibacterial activity-a mini-review

GŞ Andrei, BF Andrei… - Mini Reviews in Medicinal …, 2021 - ingentaconnect.com
Background: The development of drug resistance by bacterial strains is a public health
issue, being the main cause of the decrease in the effectiveness of numerous antibiotics. In …