Alternative polyadenylation (APA) is a molecular mechanism during a pre‐mRNA
processing that involves usage of more than one polyadenylation site (PA‐site) generating …

ABSTRACT A protein called cleavage-stimulating factor subunit 2 (CSTF2, additionally
called CSTF-64) binds RNA and is needed for the cleavage and polyadenylation of mRNA …

Genes that are involved in the transcription process, mitochondrial function, glycoprotein
metabolism, and ubiquitination dominate the list of 21 new genes associated with X‐linked …

Differential polyadenylation sites (PAs) critically regulate gene expression, but their cell type–
specific usage and spatial distribution in the brain have not been systematically …

The integrated stress response is a network of highly orchestrated pathways activated when
cells are exposed to environmental stressors. While global repression of translation is a well …

Balanced mRNA isoform diversity and abundance are spatially and temporally regulated
throughout cellular differentiation. The proportion of expressed isoforms contributes to cell …

Cleavage stimulation factor subunit 2 (CSTF2) is a fundamental factor in the regulation of
3′-end cleavage and alternative polyadenylation of pre-mRNAs. Previous work has …

The RNA recognition motif (RRM) is a conserved and ubiquitous RNA-binding domain that
plays essential roles in mRNA splicing, polyadenylation, transport, and stability. RRM …

Background Cleavage stimulation factor 2 (CSTF2) encodes a nuclear protein that is
implicated in the development of various cancers. However, the role of CSTF2 in …

Background/Objectives: Developmental and epileptic encephalopathy 9 (DEE9)(MIM#
300088) affects heterozygous females and males with somatic pathogenic variants, while …