It is well known that lifestyle changes can alter several physiological functions in the human
body. For exercise and diet, these effects are used sensibly in basic therapies, as in …

Warfarin is the most commonly used oral anticoagulant in sub‐Saharan Africa. Dosing is
challenging due to a narrow therapeutic index and high interindividual variability in dose …

Objective We assessed the influence of age on warfarin dose, percentage time in target
range (PTTR), and risk of major hemorrhage. Design Warfarin users recruited into a large …

Background: Atrial Fibrillation (AF) is the most common sustained cardiac arrhythmia.
Obesity is an independent risk factor for AF. Anticoagulants have been strongly …

Many clinicians increasingly use dry needling in clinical practice. However, whether patients'
intake of antithrombotic drugs should be considered as a contraindication for dry needling …

Objective We evaluated whether percent time in target range (PTTR), risk of over-
anticoagulation [international normalized ratio (INR)> 4], and risk of hemorrhage differ by …

A lack in patient knowledge of warfarin therapy is associated with poor adherence. This
knowledge gap may result in a lower INR Time in Therapeutic Range (TTR). To investigate …

Exercise significantly alters human physiological functions, such as increasing cardiac
output and muscle blood flow and decreasing glomerular filtration rate (GFR) and liver blood …

Warfarin is an oral anticoagulant agent with a narrow therapeutic index. There is a marked
inter-and intra-patient variability in warfarin dose requirement. All factors influencing warfarin …

Vitamin K antagonists (VKAs) are used in the prophylaxis and treatment of thromboembolic
disorders. Despite a high efficacy, their narrow therapeutic window and high response …