Tortuous arteries and veins are commonly observed in humans and animals. While mild
tortuosity is asymptomatic, severe tortuosity can lead to ischemic attack in distal organs …

Abstract Introduction Loeys-Dietz syndrome (LDS) is a connective tissue disorder that arises
from mutations altering the transforming growth factor β signalling pathway. Due to the …

ABSTRACT Introduction: The revised Ghent nosology presents the classical features of
Marfan syndrome. However, behind its familiar face, Marfan syndrome hides less well …

Arterial tortuosity is commonly present in genetically mediated aortic disease. Given the
suboptimal performance of aortic dimension alone in predicting aortic dissection …

Objective Spontaneous cervicocerebral artery dissection (sCCD) is an important cause of
ischaemic stroke that often occurs in young and middle aged patients. The purpose of this …

BACKGROUND AND PURPOSE: The association of arterial tortuosity and connective tissue
diseases is widely reported in the literature, but only a few studies were based on a …

Loeys-Dietz syndrome (LDS) is an increasingly recognized autosomal-dominant connective
tissue disorder with distinctive radiological manifestations, including arterial …

Patients with connective tissue diseases (CTDs) are suspected to be at higher risk for
cerebrovascular involvement, such as intracranial aneurysms, dissections and strokes, than …

Objective This study aimed to determine if carotid arterial tortuosity represents a marker of
disease severity in Loeys-Dietz syndrome (LDS). Methods Fifty-four 54 LDS patients (mean …

Background and Purpose Dural ectasia is well recognized in Marfan syndrome (MFS) as
one of the major diagnostic criteria, but the exact prevalence of dural ectasia is still unknown …