Background Exercise programmes are a relatively inexpensive, low‐risk option compared
with other, more invasive therapies for treatment of leg pain on walking (intermittent …

Background Intermittent claudication (IC) is a common and debilitating symptom of
peripheral arterial disease and is associated with a significant reduction in a sufferer's …

Carnitine derivatives: clinical usefulness : Current Opinion in Gastroenterology Carnitine
derivatives: clinical usefulness : Current Opinion in Gastroenterology Log in or Register …

Abstract Propionyl-L-carnitine (PLC) is a naturally occurring derivative of carnitine that plays
an important role in the metabolism of both carbohydrates and lipids, leading to an increase …

Acetyl-L-carnitine (ALC) and propionyl-L-carnitine (PLC) are two naturally occurring
carnitine derivates formed by carnitine acetyltransferase. The beneficial cardiovascular …

METHODS This study was a randomized, placebo-controlled, double-blinded, multicenter
trial conducted at 10 sites in the United States, from May 2006 through March 2008. The …

Perfluorooctanoic acid (PFOA) is a persistent organic pollutant. This study established an in
ovo peroxisome proliferator-activated receptor alpha (PPAR alpha) silencing model in …

OBJECTIVE: To evaluate the evidence for the use of carnitine supplementation in improving
walking performance among individuals with intermittent claudication. DESIGN: Systematic …

Background & aim Ischemia-reperfusion (I/R) injury plays important role in morbidity and
mortality in several pathologies, including myocardial infarction, ischemic stroke, acute …

Peripheral arterial disease (PAD) is a clinical manifestation of underlying aorto-iliac and leg
atherosclerosis that is characterized by different stages of stenosis and obstruction. It affects …