Brain functional and structural magnetic resonance imaging of obesity and weight loss interventions

G Li, Y Hu, W Zhang, J Wang, W Ji, P Manza… - Molecular …, 2023 - nature.com
Obesity has tripled over the past 40 years to become a major public health issue, as it is
linked with increased mortality and elevated risk for various physical and neuropsychiatric …

Body–brain connections: The effects of obesity and behavioral interventions on neurocognitive aging

CM Stillman, AM Weinstein, AL Marsland… - Frontiers in aging …, 2017 - frontiersin.org
Obesity is a growing public health problem in the United States, particularly in middle-aged
and older adults. Although the key factors leading to a population increase in body weight …

Obesity as a risk factor for accelerated brain ageing in first-episode psychosis—a longitudinal study

S McWhinney, M Kolenic, K Franke… - Schizophrenia …, 2021 - academic.oup.com
Background Obesity is highly prevalent in schizophrenia, with implications for psychiatric
prognosis, possibly through links between obesity and brain structure. In this longitudinal …

Obesity, dyslipidemia and brain age in first-episode psychosis

M Kolenic, K Franke, J Hlinka, M Matejka… - Journal of psychiatric …, 2018 - Elsevier
Introduction Obesity and dyslipidemia may negatively affect brain health and are frequent
medical comorbidities of schizophrenia and related disorders. Despite the high burden of …

Treatment with a GLP− 1R agonist over four weeks promotes weight loss-moderated changes in frontal-striatal brain structures in individuals with mood disorders

RB Mansur, A Zugman, J Ahmed, DS Cha… - European …, 2017 - Elsevier
Cognitive deficits are a core feature across psychiatric disorders. Emerging evidence
indicates that metabolic pathways are highly relevant for the substrates and phenomenology …

Patterns of regional cerebral blood flow as a function of obesity in adults

DG Amen, J Wu, N George… - Journal of Alzheimer's …, 2020 - content.iospress.com
Background: While obesity has been shown to be a risk factor for Alzheimer's disease, the
potential mechanisms underlying this risk may be clarified with better understanding of …

[HTML][HTML] Efficacy of weight loss intervention can be predicted based on early alterations of fMRI food cue reactivity in the striatum

P Hermann, V Gál, I Kóbor, CB Kirwan, P Kovács… - NeuroImage: Clinical, 2019 - Elsevier
Increased fMRI food cue reactivity in obesity, ie higher responses to high-vs. low-calorie
food images, is a promising marker of the dysregulated brain reward system underlying …

[HTML][HTML] Obesity is associated with reduced orbitofrontal cortex volume: a coordinate-based meta-analysis

EY Chen, SB Eickhoff, T Giovannetti, DV Smith - NeuroImage: Clinical, 2020 - Elsevier
Neural models of obesity vary in their focus upon prefrontal and striatal differences. Animal
and human studies suggest that differential functioning of the orbitofrontal cortex is …

Neuroimaging Investigations of Obesity: a Review of the Treatment of Sex from 2010

LA Kilpatrick, HM An, S Pawar, R Sood, A Gupta - Current obesity reports, 2023 - Springer
Abstract Purpose of Review To summarize the results of adult obesity neuroimaging studies
(structural, resting-state, task-based, diffusion tensor imaging) published from 2010, with a …

The Obese Brain

S Carmo-Silva, C Nóbrega - Obesity: Clinical, Surgical and Practical Guide, 2024 - Springer
This chapter explores the complex relationship between the brain and body weight
regulation, focusing on the disruptive impact of obesity. The brain, specifically the …