Modeling menopause: The utility of rodents in translational behavioral endocrinology research

SV Koebele, HA Bimonte-Nelson - Maturitas, 2016 - Elsevier
The human menopause transition and aging are each associated with an increase in a
variety of health risk factors including, but not limited to, cardiovascular disease …

Multi-target strategies for the improved treatment of depressive states: conceptual foundations and neuronal substrates, drug discovery and therapeutic application

MJ Millan - Pharmacology & therapeutics, 2006 - Elsevier
Major depression is a debilitating and recurrent disorder with a substantial lifetime risk and a
high social cost. Depressed patients generally display co-morbid symptoms, and depression …

Estrogen therapy and cognition: a review of the cholinergic hypothesis

RB Gibbs - Endocrine reviews, 2010 - academic.oup.com
The pros and cons of estrogen therapy for use in postmenopausal women continue to be a
major topic of debate in women's health. Much of this debate focuses on the potential …

Neurobiological underpinnings of the estrogen-mood relationship

W Wharton, CE Gleason, O Sandra… - Current psychiatry …, 2012 - ingentaconnect.com
Women are at a higher risk than men to develop mood disorders and depression. The
increased risk is associated with fluctuating estrogen levels that occur during reproductive …

In utero exposure to background concentrations of DDT and cognitive functioning among preschoolers

N Ribas-Fito, M Torrent, D Carrizo… - American journal of …, 2006 - academic.oup.com
Abstract p, p′-DDT (bis [p-chlorophenyl]-1, 1, 1-trichloroethane) is a persistent
organochlorine compound that has been used worldwide as an insecticide. The authors …

Estrogens, estrogen receptors, and female cognitive aging: the impact of timing

JM Daniel - Hormones and behavior, 2013 - Elsevier
This article is part of a Special Issue" Hormones & Neurotrauma". Estrogens have been
shown to be protective agents against neurodegeneration and associated cognitive decline …

Perspectives on fear generalization and its implications for emotional disorders

AM Jasnow, JF Lynch III, TL Gilman… - Journal of …, 2017 - Wiley Online Library
Although generalization to conditioned stimuli is not a new phenomenon, renewed interest
in understanding its biological underpinning has stemmed from its association with a …

Estrogen–cholinergic interactions: implications for cognitive aging

P Newhouse, J Dumas - Hormones and behavior, 2015 - Elsevier
This article is part of a Special Issue “Estradiol and Cognition”. While many studies in
humans have investigated the effects of estrogen and hormone therapy on cognition …

Progesterone reverses the spatial memory enhancements initiated by tonic and cyclic oestrogen therapy in middle‐aged ovariectomized female rats

HA Bimonte‐Nelson, KR Francis… - European Journal of …, 2006 - Wiley Online Library
While some research has indicated that ovarian hormone therapy (HT) benefits memory and
decreases risk of Alzheimer's disease in menopausal women, several newer studies have …

Effects of oestrogen on cognition: what have we learned from basic research?

JM Daniel - Journal of neuroendocrinology, 2006 - Wiley Online Library
The results of clinical and basic research conducted over the past two decades have
implicated a role for oestrogen in modulating cognitive function. This review focuses on what …