Traumatic brain injury: Mechanisms, manifestations, and visual sequelae

SH Rauchman, A Zubair, B Jacob… - Frontiers in …, 2023 - frontiersin.org
Traumatic brain injury (TBI) results when external physical forces impact the head with
sufficient intensity to cause damage to the brain. TBI can be mild, moderate, or severe and …

[HTML][HTML] Chloride ion dysregulation in epileptogenic neuronal networks

SA Weiss - Neurobiology of Disease, 2023 - Elsevier
GABA is the major inhibitory neurotransmitter in the mature CNS. When GABA A receptors
are activated the membrane potential is driven towards hyperpolarization due to chloride …

[HTML][HTML] Mouse model of focal cortical dysplasia type II generates a wide spectrum of high-frequency activities

J Chvojka, N Prochazkova, M Rehorova… - Neurobiology of …, 2024 - Elsevier
High-frequency oscillations (HFOs) represent an electrographic biomarker of endogenous
epileptogenicity and seizure-generating tissue that proved clinically useful in presurgical …

Pathological and physiological high-frequency oscillations on electroencephalography in patients with epilepsy

H Ye, C Chen, SA Weiss, S Wang - Neuroscience Bulletin, 2024 - Springer
High-frequency oscillations (HFOs) encompass ripples (80 Hz–200 Hz) and fast ripples (200
Hz–600 Hz), serving as a promising biomarker for localizing the epileptogenic zone in …

Insights into epileptogenesis from post-traumatic epilepsy

M Pease, K Gupta, SL Moshé, DJ Correa… - Nature Reviews …, 2024 - nature.com
Post-traumatic epilepsy (PTE) accounts for 5% of all epilepsies. The incidence of PTE after
traumatic brain injury (TBI) depends on the severity of injury, approaching one in three in …

Pathological neurons generate ripples at the UP‐DOWN transition disrupting information transfer

SA Weiss, I Fried, J Engel Jr, A Bragin, S Wang… - …, 2024 - Wiley Online Library
Objective To confirm and investigate why pathological high‐frequency oscillations (pHFOs),
including ripples (80–200 Hz) and fast ripples (200–600 Hz), are generated during the UP …

How Can I Disentangle Physiological and Pathological High-Frequency Oscillations?

B Frauscher, J Gotman - Intracranial EEG: A Guide for Cognitive …, 2023 - Springer
High-frequency oscillations (HFOs) consist of ripples (80–250 Hz) and fast ripples (> 250
Hz). Ripples are attributed an important role in cognition, sleep, and task-related processes …

Graph theoretical measures of fast ripple networks improve the accuracy of post-operative seizure outcome prediction

SA Weiss, I Fried, C Wu, A Sharan, D Rubinstein… - Scientific Reports, 2023 - nature.com
Fast ripples (FR) are a biomarker of epileptogenic brain, but when larger portions of FR
generating regions are resected seizure freedom is not always achieved. To evaluate and …

Electrically-evoked oscillating calcium transients in mono-and co-cultures of iPSC glia and sensory neurons

J Lawson, E LaVancher, M DeAlmeida… - Frontiers in Cellular …, 2023 - frontiersin.org
Activated glia are known to exhibit either neuroprotective or neurodegenerative effects,
depending on their phenotype, while participating in chronic pain regulation. Until recently, it …

Preventive effects of transcranial photobiomodulation on epileptogenesis in a kainic acid-induced rat epilepsy model

J You, J Fuchs, M Wang, Q Hu, X Tao, E Krolczyk… - Experimental …, 2025 - Elsevier
Objective Temporal lobe epilepsy affects nearly 50 million people worldwide and is a major
burden to families and society. A significant portion of patients are living in developing …