Acquired hemophilia A as a disease of the elderly: A comprehensive review of epidemiology, pathogenesis, and novel therapy

A Lehoczki, M Fekete, G Mikala, I Bodó - Geroscience, 2024 - Springer
Acquired hemophilia A (AHA) is a rare autoimmune bleeding disorder characterized by the
development of neutralizing autoantibodies (inhibitors) against coagulation factor VIII (FVIII) …

Acquired hemophilia A after SARS-CoV-2 immunization: a narrative review of a rare side effect

R Castelli, A Gidaro, R Manetti, P Castiglia, AP Delitala… - vaccines, 2024 - mdpi.com
Acquired hemophilia A (AHA) is a rare bleeding disorder (1.4 per million inhabitants per
year) caused by neutralizing antibodies against factor VIII. Although uncommon, these …

[HTML][HTML] Acquired hemophilia A post-COVID-19 vaccination: a case report and review

H Al Hennawi, MK Al Masri, M Bakir, M Albarazi… - Cureus, 2022 - ncbi.nlm.nih.gov
Acquired hemophilia A (AHA) is an inhibitory coagulopathy that represents a rare variant of
hemorrhagic syndromes. We present a case of idiopathic AHA in a 75-year-old male patient …

A diagnostic of acquired hemophilia following PD1/PDL1 inhibitors in advanced melanoma: the experience of two patients and a literature review

A Gidaro, G Palmieri, M Donadoni, LA Mameli… - Diagnostics, 2022 - mdpi.com
Acquired hemophilia A (AHA) is a rare bleeding disorder caused by the development of
specific autoantibodies against factor VIII (FVIII). Immunotherapy is a recent therapeutic …

Current status and future prospects of activated recombinant coagulation factor VIIa, NovoSeven®, in the treatment of haemophilia and rare bleeding disorders

M Shima - Annals of Hematology, 2024 - Springer
Abstract rFVIIa, a human recombinant activated coagulation factor VII, has been used
worldwide for more than two decades for the treatment of bleeding episodes and prevention …

Outcomes of Emicizumab in Acquired Hemophilia Patients: A Systematic Review

G Ikbel, B Hela, KM Yassine… - Clinical and Applied …, 2024 - journals.sagepub.com
Background Emicizumab, a bispecific factor VIII mimetic antibody, was approved in 2018 for
bleeding prophylaxis in congenital hemophilia A with or without inhibitors. Since then …

Acquired hemophilia A (AHA) due to anti‐SARS‐CoV‐2 vaccination: A systematic review

F Amisha, P Saluja, P Malik, F Van Rhee - EJHaem, 2023 - Wiley Online Library
Vaccination against SARS‐CoV2 has been the largest vaccination campaign over the past
two decades. The aim of this study is to qualitatively assess the reported cases of acquired …

[HTML][HTML] The Impact of recombinant versus plasma-derived factor VIII concentrates on inhibitor development in previously untreated patients with hemophilia A: a 2021 …

K Kohar, SA Prayogo, L Wiyono - Cureus, 2022 - ncbi.nlm.nih.gov
Hemophilia A, the most common hereditary disorder, is caused by clotting factor deficiency.
Challenges encountered in the current treatment of hemophilia A [factor VIII (FVIII) …

Diagnosis and management of acquired hemophilia a: case reports and a literature review

I Rinaldi, F Prasetyawaty, S Fazlines… - Case reports in …, 2021 - Wiley Online Library
Background. Acquired hemophilia A (AHA) is a potentially life‐threatening autoimmune
hemostatic disorder where autoantibodies that disrupt the functions of factor VIII (FVIII) are …

Genetics and Epigenetics in Acquired Hemophilia A: From Bench to Bedside

N Evangelidis, N Kotsiou, P Evangelidis… - Current Issues in …, 2024 - mdpi.com
Acquired hemophilia A (AHA) is a bleeding disorder characterized by the immunological
inhibition of factor VIII (FVIII) of the hemostatic pathway leading to hemorrhagic events …