Does vertebral osteoporosis delay or accelerate lumbar disc degeneration? A systematic review

W Li, H Zhao, S Zhou, Z Xiong, W Zhong, J Guan… - Osteoporosis …, 2023 - Springer
The effect of vertebral osteoporosis on disc degeneration is still debated. The purpose of this
study was to provide a systematic review of studies in this area to further reveal the …

Animal models for glucocorticoid-induced postmenopausal osteoporosis: An updated review

Z Zhang, H Ren, G Shen, T Qiu, D Liang, Z Yang… - Biomedicine & …, 2016 - Elsevier
Glucocorticoid-induced postmenopausal osteoporosis is a severe osteoporosis, with high
risk of major osteoporotic fractures. This severe osteoporosis urges more extensive and …

Relevant anatomic and morphological measurements of the rat spine: considerations for rodent models of human spine trauma

NV Jaumard, J Leung, AJ Gokhale, BB Guarino… - Spine, 2015 - journals.lww.com
Study Design. Basic science study measuring anatomical features of the cervical and lumbar
spine in rat with normalized comparison with the human. Objective. The goal of this study is …

Estrogen deficiency exacerbates intervertebral disc degeneration induced by spinal instability in rats

Q Liu, X Wang, Y Hua, G Kong, X Wu, Z Huang… - Spine, 2019 - journals.lww.com
Study Design. An experimental animal study of osteoporosis (OP) and intervertebral disc
degeneration (IDD). Objective. The aim of this study was to clarify the effects of estrogen …

[HTML][HTML] Biomechanical evaluation of an osteoporotic anatomical 3D printed posterior lumbar interbody fusion cage with internal lattice design based on weighted …

SF Huang, CM Chang, CY Liao, YT Chan… - … Journal of Bioprinting, 2023 - ncbi.nlm.nih.gov
In this study, we designed and manufactured a posterior lumbar interbody fusion cage for
osteoporosis patients using 3D-printing. The cage structure conforms to the anatomical …

Sdc4 deletion perturbs intervertebral disc matrix homeostasis and promotes early osteopenia in the aging mouse spine

K Sao, MV Risbud - Matrix Biology, 2024 - Elsevier
Abstract Syndecan 4 (Sdc4), a cell surface heparan sulfate proteoglycan, is known to
regulate matrix catabolism by nucleus pulposus cells in an inflammatory milieu. However …

New evidence on the controversy over the correlation between vertebral osteoporosis and intervertebral disc degeneration: a systematic review of relevant animal …

W Li, Y Niu, Z Qiu, S Zhou, W Zhong, Z Xiong… - European Spine …, 2024 - Springer
Objective The effect of vertebral osteoporosis on disc degeneration remains controversial.
The aim of this study was to conduct a systematic review and meta-analysis of relevant …

[HTML][HTML] The Relationship Between Bone Mineral Density and Lumbar Disc Herniation in Postmenopausal Women

ZE Çelen, T Onay - Cureus, 2023 - ncbi.nlm.nih.gov
Introduction: In previous studies, the relationship between BMD (bone mineral density) and
LDH (lumbar disc herniation) has been investigated in young people, except for …

Assessment of lumbar vertebrae morphology by computed tomography in older adults with osteoporosis

CY Liao, CL Chien, TW Pu, SC Shen… - Current Medical …, 2022 - ingentaconnect.com
Background: Hounsfield Units (HU) values derived from Computerized Tomography (CT)
have been used in the diagnosis of osteoporosis in the lumbar spine. Objective: This study …

Repression of let‐7b‐5p prevents the development of multifidus muscle dysfunction by promoting vitamin D accumulation via upregulation of electron transfer …

HM Yu, XD Yao, RM Zhang, HF Zhuang… - Journal of Cellular …, 2019 - Wiley Online Library
Multifidus muscle dysfunction is associated with the multifidus muscle injury (MMI), which
ultimately result in the low‐back pain. Increasing evidence shows that microRNAs (miRs) …