Infections represent a common health problem in people of all ages. Usually, the response
given to them is appropriate and so little treatment is needed. Sometimes, however, the …

Background The time course of blood lactate levels could be helpful to assess a patient's
response to therapy. Although the focus of published studies has been largely on septic …

Background Elevated lactate has been found to be associated with a higher mortality in a
diverse patient population. The aim of the study is to investigate if initial serum lactate level …

Objective: To measure the relationship between lactate and mortality in hospital inpatients.
Main outcomes of interest were 3-day, 30-day, and 1-year all-cause mortality. Design …

Sepsis is a common disease process encountered by physicians. Sepsis can lead to septic
shock, which carries a hospital mortality rate in excess of 40%. Although the Surviving …

Abstract On October 1, 2015, the United States Centers for Medicare and Medicaid Services
(CMS) issued a core measure addressing the care of septic patients. These core measures …

The purpose of this study was to confirm the prognostic value of pentraxin-3 (PTX3),
procalcitonin (PCT) and lactate in patients with severe infections requiring ICU management …

Abstract In April 2018, the Surviving Sepsis Campaign (SSC) released an updated sepsis
bundle, which combines directives previously listed in the three-hour and six-hour bundles …

Background Sepsis is a potentially fatal condition with high treatment costs, and is especially
common among the elderly population. The emergency management of septic patients has …

The use of lactate as a marker of the severity of circulatory shock was popularized by Dr.
Weil in the 1970's. Dr. Weil promoted the idea that blood lactate concentration increased in …