Exosomes are a type of extracellular vesicles, produced within multivesicular bodies, that
are then released into the extracellular space through a merging of the multivesicular body …

Cell-based therapy holds great potential to address unmet medical needs and revolutionize
the healthcare industry, as demonstrated by several therapeutics such as CAR-T cell …

Stem cell-based therapy has drawn attention for enhancing the osseointegration efficiency
after joint replacement in the rheumatoid arthritis (RA). However, therapeutic efficacy of this …

Exosomes are extracellular vesicles with a diameter ranging from 30 to 150 nm, which are
an important medium for intercellular communication and are closely related to the …

As the global population ages, bone‐related diseases have increasingly become a major
social problem threatening human health. Exosomes, as natural cell products, have been …

Osteoarthritis (OA) is a prevalent chronic whole-joint disease characterized by low-grade
systemic inflammation, degeneration of joint-related tissues such as articular cartilage, and …

Traditionally, organic chemical reactions require organic solvents, toxic catalysts, heat, or
high pressure. However, copper‐free click chemistry has been shown to have favorable …

Effective countermeasures for tendon injury remains unsatisfactory. Mesenchymal stem cell-
derived extracellular vesicles (MSC-EVs)-based therapy via regulation of Mφ-mediated …

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by synovitis and
destruction of cartilage, promoted by sustained inflammation. However, current treatments …

In recent decades, extracellular vesicles (EVs), as bioactive cell-secreted nanoparticles
which are involved in various physiological and pathological processes including cell …