Interaction between virus-like particles (VLPs) and pattern recognition receptors (PRRs) from dendritic cells (DCs): toward better engineering of VLPs

J Zepeda-Cervantes, JO Ramírez-Jarquín… - Frontiers in …, 2020 - frontiersin.org
Virus-like particles (VLPs) have been shown to be strong activators of dendritic cells (DCs).
DCs are the most potent antigen presenting cells (APCs) and their activation prompts the …

Epithelial cell responses to infection with human papillomavirus

MA Stanley - Clinical microbiology reviews, 2012 - Am Soc Microbiol
Human papillomavirus (HPV) infection of the genital tract is common in young sexually
active individuals, the majority of whom clear the infection without overt clinical disease …

AS04, an aluminum salt-and TLR4 agonist-based adjuvant system, induces a transient localized innate immune response leading to enhanced adaptive immunity

AM Didierlaurent, S Morel, L Lockman… - The Journal of …, 2009 - journals.aai.org
Abstract Adjuvant System 04 (AS04) combines the TLR4 agonist MPL (3-O-desacyl-4′-
monophosphoryl lipid A) and aluminum salt. It is a new generation TLR-based adjuvant …

[图书][B] Human papillomaviruses

IARC Working Group on the Evaluation of … - 2007 - books.google.com
This ninetieth volume of the IARC Monographs on the Evaluation of Carcinogenic Risks to
Humansconsiders human papillomaviruses (HPVs) which were evaluated by a previous …

Immunobiology of HPV and HPV vaccines

M Stanley - Gynecologic oncology, 2008 - Elsevier
Genital human papillomavirus (HPV) infection with both low-and high-risk types is common,
but most infections resolve as a result of a cell-mediated immune response. Failure to …

Prophylactic HPV vaccines: underlying mechanisms

M Stanley, DR Lowy, I Frazer - Vaccine, 2006 - Elsevier
Human papillomavirus virus-like particles (HPV VLP) can be generated by the synthesis and
self-assembly in vitro of the major virus capsid protein L1. HPV L1 VLPs are morphologically …

Different applications of virus‐like particles in biology and medicine: vaccination and delivery systems

Z Shirbaghaee, A Bolhassani - Biopolymers, 2016 - Wiley Online Library
Virus‐like particles (VLPs) mimic the whole construct of virus particles devoid of viral
genome as used in subunit vaccine design. VLPs can elicit efficient protective immunity as …

Antiphospholipid antibodies induce a pro‐inflammatory response in first trimester trophoblast via the TLR4/MyD88 pathway

MJ Mulla, JJ Brosens, LW Chamley… - American Journal of …, 2009 - Wiley Online Library
Problem Women with antiphospholipid antibodies (aPL) are at risk for recurrent miscarriage,
pre‐eclampsia, and pre‐term labor. aPL target the placenta directly by binding to beta2 …

Immune responses to human papilloma viruses

MA Stanley - Indian Journal of Medical Research, 2009 - journals.lww.com
HPV infection in the genital tract is common in young sexually active individuals, the majority
of whom clear the infection without overt clinical disease. However most of those who …

Single-dose HPV vaccine immunity: is there a role for non-neutralizing antibodies?

C Quang, AW Chung, IH Frazer, ZQ Toh… - Trends in …, 2022 - cell.com
A single dose of human papillomavirus (HPV) vaccine against HPV infection (prerequisite
for cervical cancer) appears to be as efficacious as two or three doses, despite inducing …