Radiopharmaceutical therapy in cancer: clinical advances and challenges

G Sgouros, L Bodei, MR McDevitt… - Nature reviews Drug …, 2020 - nature.com
Radiopharmaceutical therapy (RPT) is emerging as a safe and effective targeted approach
to treating many types of cancer. In RPT, radiation is systemically or locally delivered using …

Consensus on molecular imaging and theranostics in neuroendocrine neoplasms

V Ambrosini, J Kunikowska, E Baudin, L Bodei… - European journal of …, 2021 - Elsevier
Nuclear medicine plays an increasingly important role in the management neuroendocrine
neoplasms (NEN). Somatostatin analogue (SSA)-based positron emission …

[HTML][HTML] Gastroenteropancreatic neuroendocrine neoplasms: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

M Pavel, K Öberg, M Falconi, EP Krenning, A Sundin… - Annals of …, 2020 - Elsevier
Neuroendocrine neoplasms (NENs) arise from the diffuse neuroendocrine cell system and
may occur at many different disease sites. Most frequently, these neoplasms occur in the …

Trends in the incidence, prevalence, and survival outcomes in patients with neuroendocrine tumors in the United States

A Dasari, C Shen, D Halperin, B Zhao, S Zhou… - JAMA …, 2017 - jamanetwork.com
Importance The incidence and prevalence of neuroendocrine tumors (NETs) are thought to
be rising, but updated epidemiologic data are lacking. Objective To explore the evolving …

Phase 3 Trial of 177Lu-Dotatate for Midgut Neuroendocrine Tumors

J Strosberg, G El-Haddad, E Wolin… - … England Journal of …, 2017 - Mass Medical Soc
Background Patients with advanced midgut neuroendocrine tumors who have had disease
progression during first-line somatostatin analogue therapy have limited therapeutic options …

The North American Neuroendocrine Tumor Society consensus paper on the surgical management of pancreatic neuroendocrine tumors

JR Howe, NB Merchant, C Conrad, XM Keutgen… - Pancreas, 2020 - journals.lww.com
This manuscript is the result of the North American Neuroendocrine Tumor Society
consensus conference on the surgical management of pancreatic neuroendocrine tumors …

ENETS consensus guidelines update for the management of patients with functional pancreatic neuroendocrine tumors and non-functional pancreatic neuroendocrine …

M Falconi, B Eriksson, G Kaltsas, DK Bartsch… - …, 2016 - karger.com
Only advances that occurred from 2011 to 2014 that either strengthen the previous 2011
guidelines [1, 2] or lead to changes or additional guidelines are reviewed here. Advances …

ENETS consensus guidelines update for the management of distant metastatic disease of intestinal, pancreatic, bronchial neuroendocrine neoplasms (NEN) and NEN …

M Pavel, D O''Toole, F Costa, J Capdevila… - …, 2016 - karger.com
M. Pavel a D. O'Toole b F. Costa c J. Capdevila d D. Gross e R. Kianmanesh f E. Krenning g
U. Knigge h R. Salazar i U.-F. Pape a K. Öberg j all other Vienna Consensus Conference …

Long-Term Efficacy, Survival, and Safety of [177Lu-DOTA0,Tyr3]octreotate in Patients with Gastroenteropancreatic and Bronchial Neuroendocrine Tumors

T Brabander, WA van der Zwan, JJM Teunissen… - Clinical Cancer …, 2017 - AACR
Purpose: Bronchial and gastroenteropancreatic neuroendocrine tumors (NET) are slow-
growing tumors, which frequently express somatostatin receptors on their cell membranes …

Targeted α-emitter therapy with 212Pb-DOTAMTATE for the treatment of metastatic SSTR-expressing neuroendocrine tumors: first-in-humans dose-escalation clinical …

ES Delpassand, I Tworowska… - Journal of Nuclear …, 2022 - Soc Nuclear Med
Peptide receptor radiotherapy with somatostatin analogs has been successfully used for
years as a treatment for somatostatin-overexpressing tumors. Treatment of neuroendocrine …