SARS-CoV-2 infection is benign in most individuals but, in around 10% of cases, it triggers
hypoxaemic COVID-19 pneumonia, which leads to critical illness in around 3% of cases …

Children and adolescents exhibit a broad range of clinical outcomes from SARS-CoV-2
infection, with the majority having minimal to mild symptoms. Additionally, some succumb to …

Recessive or dominant inborn errors of type I interferon (IFN) immunity can underlie critical
COVID-19 pneumonia in unvaccinated adults. The risk of COVID-19 pneumonia in …

Disclosures: C. Flores reported grants from Instituto de Salud Carlos III, Spanish Ministry of
Science and Innovation, and Cabildo Insular de Tenerife outside the submitted work. J …

Objective We aimed to look at the burden of disease caused by SARS-COV-2 reinfections
and identified potential risk factors for disease severity. Methods We used national …

Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the causative agent of
coronavirus disease 2019 (COVID‐19), has caused millions of deaths in the past two years …

Since the start of the coronavirus disease 2019 (COVID-19) pandemic, important insights
have been gained into virus biology and the host factors that modulate the human immune …

A male sex bias has emerged in the COVID-19 pandemic, fitting to the sex-biased pattern in
other viral infections. Males are 2.84 times more often admitted to the ICU and mortality is …

The coronavirus 2019 (COVID-19) pandemic was caused by a positive sense single-
stranded RNA (ssRNA) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) emerged at the end of
2019 and caused the pandemic of coronavirus disease 2019 (COVID-19). Basic and clinical …