A systematic review of hepatitis B virus (HBV) drug and vaccine escape mutations in Africa: A call for urgent action

J Mokaya, AL McNaughton, MJ Hadley… - PLoS neglected …, 2018 - journals.plos.org
International sustainable development goals for the elimination of viral hepatitis as a public
health problem by 2030 highlight the pressing need to optimize strategies for prevention …

Hepatitis B virus research in South Africa

MB Maepa, A Ely, A Kramvis, K Bloom, K Naidoo… - Viruses, 2022 - mdpi.com
Despite being vaccine-preventable, hepatitis B virus (HBV) infection remains the seventh
leading cause of mortality in the world. In South Africa (SA), over 1.9 million people are …

Genetic diversity of hepatitis B virus quasispecies in different biological compartments reveals distinct genotypes

BV do Lago, CS Bezerra, DA Moreira, TE Parente… - Scientific Reports, 2023 - nature.com
The selection pressure imposed by the host immune system impacts hepatitis B virus (HBV)
quasispecies variability. This study evaluates HBV genetic diversity in different biological …

Guidelines for the vaccination of HIV-infected adolescents and adults in South Africa

SK Dlamini, SA Madhi, R Muloiwa… - … African Journal of HIV …, 2018 - journals.co.za
The introduction of vaccines has been one of the most cost-effective strategies to prevent
infectious diseases in humans. It is estimated that vaccines save 2–3 million lives globally …

Investigating drug and vaccine resistance as a challenge for hepatitis B virus elimination in Africa

J Mokaya - 2020 - ora.ox.ac.uk
Background The United Nations Sustainable Development Goals set out to eliminate viral
hepatitis by the year 2030. However, hepatitis B virus (HBV) drug resistance-associated …

HBV viral load and drug resistance among HIV-HBV co-infected patients: a cross-sectional study in central South Africa

JC Kotze - 2021 - scholar.ufs.ac.za
Abstract In South Africa, human immunodeficiency virus (HIV) infected individuals co-
infected with hepatitis B virus (HBV) do not routinely undergo HBV viral load (VL) testing …