Ferroptosis is a form of regulated cell death that is initiated by excessive lipid peroxidation
that results in plasma membrane damage and the release of damage-associated molecular …

Ferroptosis is a novel form of regulated cell death (RCD) that is typically accompanied by
iron accumulation and lipid peroxidation. In contrast to apoptosis, autophagy, and …

Colorectal cancer (CRC) is the leading cause of cancer-related deaths worldwide. The
limitations of current chemotherapeutic drugs in CRC include their toxicity, side effects, and …

Despite human papillomavirus vaccination and screening, in about 5% of cases, cervical
cancer (CC) is discovered at an initial metastatic stage. Moreover, nearly one-third of …

Emerging evidence on molecular biology related to tumors, inflammation, and immunity,
highlights their architectural commonality shifting cancer treatment paradigms toward more …

Gemcitabine (Gem)-based chemotherapy is one of the first-line treatments for pancreatic
ductal adenocarcinoma (PDAC). However, its clinical effect is limited due to development of …

Colorectal cancer (CRC) is one of the most frequent malignancies worldwide and remains
one of the leading causes of cancer-related deaths in the USA. The high degree of morbidity …

Ferroptosis is a type of iron-dependent programmed cell death characterized by the
dysregulation of iron metabolism and the accumulation of lipid peroxides. This nonapoptotic …

Traditional cancer treatments have posed numerous obstacles, including toxicity, multiple
drug resistance, and financial cost. On the contrary, bioactive phytochemicals used in …

Ferroptosis is a form of regulated cell death that is characterized by the accumulation of iron-
dependent lipid peroxides. The regulation of ferroptosis involves both non-enzymatic …