Graft failure after allogeneic hematopoietic stem cell transplantation

ZN Ozdemir, SC Bozdağ - Transfusion and apheresis science, 2018 - Elsevier
Graft failure is a serious complication of allogeneic hematopoietic stem cell transplantation
(allo-HSCT) defined as either lack of initial engraftment of donor cells (primary graft failure) …

[HTML][HTML] Use of thrombopoietin receptor agonists in prolonged thrombocytopenia after hematopoietic stem cell transplantation

U Mahat, SJ Rotz, R Hanna - Biology of Blood and Marrow Transplantation, 2020 - Elsevier
Prolonged thrombocytopenia after hematopoietic stem cell transplantation (HSCT) is a
strong risk factor for transplantation-related morbidity and mortality, and no standard …

[HTML][HTML] EHA guidelines on management of antithrombotic treatments in thrombocytopenic patients with cancer

A Falanga, A Leader, C Ambaglio, Z Bagoly… - …, 2022 - journals.lww.com
In cancer patients, thrombocytopenia can result from bone marrow infiltration or from
anticancer medications and represents an important limitation for the use of antithrombotic …

Eltrombopag maintains human hematopoietic stem and progenitor cells under inflammatory conditions mediated by IFN-γ

LJ Alvarado, HD Huntsman, H Cheng… - Blood, The Journal …, 2019 - ashpublications.org
The proinflammatory cytokine interferon-γ (IFN-γ) has been implicated in human
hematopoietic stem and progenitor cell (HSPC) depletion in immune-mediated bone marrow …

[HTML][HTML] Outcomes with CD34-selected stem cell boost for poor graft function after allogeneic hematopoietic stem cell transplantation: a systematic review and meta …

M Shahzad, RS Siddiqui, I Anwar… - … and Cellular Therapy, 2021 - Elsevier
Poor graft function (PGF) is a life-threatening complication after allogeneic hematopoietic
stem cell transplantation (allo-HSCT) characterized by multilineage cytopenia in the …

[HTML][HTML] Management of chemotherapy-induced thrombocytopenia: guidance from the ISTH Subcommittee on Hemostasis and Malignancy

G Soff, A Leader, H Al-Samkari, A Falanga… - Journal of Thrombosis …, 2024 - Elsevier
Thrombocytopenia is a common adverse effect of chemotherapy. The development of
chemotherapy-induced thrombocytopenia (CIT) is influenced by cancer type and therapy …

Eltrombopag for post-transplant cytopenias due to poor graft function

S Marotta, L Marano, P Ricci, F Cacace… - Bone Marrow …, 2019 - nature.com
Persistent cytopenia due to poor graft function (PoGF) is a relatively common complication
which may affect up to 20% of patients undergoing allogeneic hematopoietic stem cell …

[HTML][HTML] Thrombopoietin receptor agonists for severe thrombocytopenia after allogeneic stem cell transplantation: experience of the Spanish group of hematopoietic …

L Bento, JM Bastida, I García-Cadenas… - Biology of Blood and …, 2019 - Elsevier
Persistent thrombocytopenia is a common complication after allogeneic hematopoietic stem
cell transplantation (allo-SCT). Romiplostim and eltrombopag are the currently available …

Eltrombopag is an effective and safe therapy for refractory thrombocytopenia after haploidentical hematopoietic stem cell transplantation

H Fu, X Zhang, T Han, X Mo, Y Wang, H Chen… - Bone Marrow …, 2019 - nature.com
Refractory thrombocytopenia is a frequent and severe complication after haploidentical
allogeneic hematopoietic stem cell transplantation (haplo-HSCT) and lacks effective …

[HTML][HTML] Eltrombopag for treating thrombocytopenia after allogeneic stem cell transplantation

C Yuan, AM Boyd, J Nelson, RD Patel… - Biology of Blood and …, 2019 - Elsevier
Thrombocytopenia after allogeneic hematopoietic stem cell transplantation (allo-SCT) can
pose significant problems in management of patients. Eltrombopag is a small-molecule …