Angstrom-scale ion channels towards single-ion selectivity

H Zhang, X Li, J Hou, L Jiang, H Wang - Chemical Society Reviews, 2022 - pubs.rsc.org
Artificial ion channels with ion permeability and selectivity comparable to their biological
counterparts are highly desired for efficient separation, biosensing, and energy conversion …

Solid-state nanopore sensors

L Xue, H Yamazaki, R Ren, M Wanunu… - Nature Reviews …, 2020 - nature.com
Nanopore-based sensors have established themselves as a prominent tool for solution-
based, single-molecule analysis of the key building blocks of life, including nucleic acids …

DNA nanotechnology-enabled drug delivery systems

Q Hu, H Li, L Wang, H Gu, C Fan - Chemical reviews, 2018 - ACS Publications
Over the past decade, we have seen rapid advances in applying nanotechnology in
biomedical areas including bioimaging, biodetection, and drug delivery. As an emerging …

DNA origami: scaffolds for creating higher order structures

F Hong, F Zhang, Y Liu, H Yan - Chemical reviews, 2017 - ACS Publications
DNA has become one of the most extensively used molecular building blocks for
engineering self-assembling materials. DNA origami is a technique that uses hundreds of …

Chemistries for DNA nanotechnology

M Madsen, KV Gothelf - Chemical reviews, 2019 - ACS Publications
The predictable nature of DNA interactions enables the programmable assembly of highly
advanced 2D and 3D DNA structures of nanoscale dimensions. The access to ever larger …

Aptamer-integrated DNA nanostructures for biosensing, bioimaging and cancer therapy

HM Meng, H Liu, H Kuai, R Peng, L Mo… - Chemical Society …, 2016 - pubs.rsc.org
The combination of nanostructures with biomolecules leading to the generation of functional
nanosystems holds great promise for biotechnological and biomedical applications. As a …

Polymer nano-systems for the encapsulation and delivery of active biomacromolecular therapeutic agents

M Machtakova, H Thérien-Aubin… - Chemical society …, 2022 - pubs.rsc.org
Biomacromolecular therapeutic agents, particularly proteins, antigens, enzymes, and nucleic
acids are emerging as powerful candidates for the treatment of various diseases and the …

Solid-state nanopore systems: from materials to applications

Y He, M Tsutsui, Y Zhou, XS Miao - NPG Asia Materials, 2021 - nature.com
Ion transport and hydrodynamic flow through nanometer-sized channels (nanopores) have
been increasingly studied owing to not only the fundamental interest in the abundance of …

Highly shape-and size-tunable membrane nanopores made with DNA

Y Xing, A Dorey, L Jayasinghe, S Howorka - Nature Nanotechnology, 2022 - nature.com
Membrane nanopores are key for molecular transport in biology, portable DNA sequencing,,–
, label-free single-molecule analysis,,,,,,,,–and nanomedicine. Transport traditionally relies …

Concept and development of framework nucleic acids

Z Ge, H Gu, Q Li, C Fan - Journal of the American Chemical …, 2018 - ACS Publications
The blooming field of structural DNA nanotechnology harnessing the material properties of
nucleic acids has attracted widespread interest. The exploitation of the precise and …