Introduction: Head and neck squamous cell carcinoma (HNSCC) encompasses tumors
arising from several locations (oral and nasal cavities, paranasal sinuses, salivary glands …

Metabolomics is the systematic study of the unique chemical fingerprints of low molecular
weight endogenous metabolites or metabolite profiles in a biological sample. Metabolites …

Proteins that are important indicators of physiological or pathological states, can provide
information for the identification of early and differential markers for disease. Saliva, contains …

Efforts have been made in the last decade towards the complete characterization of saliva
proteome using gel-based and gel-free approaches. The combination of these strategies …

The annexins are a well-known, closely related, multigene superfamily of Ca2+-regulated,
phospholipid-dependent, membrane-binding proteins. As a member of the annexins, Anxa1 …

Background The saliva metabolome has been applied to explore disease biomarkers. In this
study we characterized the metabolic profile of primary Sjögren's syndrome (pSS) patients …

Cancer represents a group of heterogeneous diseases that are a leading global cause of
death. Even though mortality has decreased in the past thirty years for different reasons …

Since the emergence of high-throughput proteomic techniques and advances in clinical
technologies, there has been a steady rise in the number of cancer-associated diagnostic …

Saliva as a diagnostic fluid is gaining wider acceptance for diagnosing diseases. The
growing interest in saliva as a biological fluid is due to its noninvasiveness, easy-to-do, cost …

Comprehensive analysis and characterization of the human salivary proteome is an
important step towards the possible use of saliva for diagnostic and prognostic purposes …