Pulmonary hypertension encompasses a range of conditions directly or indirectly leading to
elevated pressures within the pulmonary arteries. Five main groups of pulmonary …

Combining existing drug therapy is essential in developing new therapeutic agents in
disease prevention and treatment. In preclinical investigations, combined effect of certain …

Cardiovascular diseases (CVDs) continue to exert a significant impact on global mortality
rates, encompassing conditions like pulmonary arterial hypertension (PAH), atherosclerosis …

The pulmonary circulation is a low-resistance, low-pressure, and high-compliance system
that allows the lungs to receive the entire cardiac output. Pulmonary arterial pressure is a …

Pulmonary hypertension is a progressive and often fatal cardiopulmonary condition
characterised by increased pulmonary arterial pressure, structural changes in the pulmonary …

Pulmonary hypertension (PH) is a serious disease characterized by various degrees of
pulmonary vasoconstriction and progressive fibroproliferative remodeling and inflammation …

Sickle cell anemia (SCA) is a hereditary blood disorder characterized by the presence of
abnormal hemoglobin, leading to the formation of sickle-shaped red blood cells. While much …

Vascular endothelial cells (ECs) are increasingly recognized as active players in
intercellular crosstalk more than passive linings of a conduit for nutrition delivery. Yet, their …

Pulmonary Hypertension (PH) is a common manifestation in patients with Systemic Lupus
Erythematosus (SLE) and varies from asymptomatic to life-threatening disease. PH can …

Background Pulmonary hypertension (PH) is a devastating disease with poor prognosis and
high mortality. Hypoxia induced pulmonary hypertension (HPH) is a persistent threat to …