Schistosomiasis and pregnancy

JF Friedman, P Mital, HK Kanzaria, GR Olds… - Trends in …, 2007 - cell.com
Currently, schistosomes infect∼ 40 million women of child-bearing age, yet little is known
about schistosome-associated morbidity in pregnant women and their offspring. Animal …

Uninfected but not unaffected: chronic maternal infections during pregnancy, fetal immunity, and susceptibility to postnatal infections

N Dauby, T Goetghebuer, TR Kollmann… - The Lancet infectious …, 2012 - thelancet.com
Chronic infections during pregnancy are highly prevalent in some parts of the world.
Infections with helminths, Trypanosoma cruzi, Plasmodium spp, and HIV might affect the …

Pregnancy and helminth infections

H Mpairwe, R Tweyongyere, A Elliott - Parasite immunology, 2014 - Wiley Online Library
It has been proposed that helminth infection may be particularly detrimental during
pregnancy, through adverse effects on maternal anaemia and on birth outcomes, and that …

Schistosoma mansoni infection alters the host pre-vaccination environment resulting in blunted Hepatitis B vaccination immune responses

R Muir, T Metcalf, S Fourati, Y Bartsch… - PLoS neglected …, 2023 - journals.plos.org
Schistosomiasis is a disease caused by parasitic flatworms of the Schistosoma spp., and is
increasingly recognized to alter the immune system, and the potential to respond to …

Immunological Considerations for Schistosoma Vaccine Development: Transitioning to Endemic Settings

E Driciru, JPR Koopman, S Cose, AA Siddiqui… - Frontiers in …, 2021 - frontiersin.org
Despite mass drug administration programmes with praziquantel, the prevalence of
schistosomiasis remains high. A vaccine is urgently needed to control transmission of this …

Maternal immune response to helminth infection during pregnancy determines offspring susceptibility to allergic airway inflammation

K Straubinger, S Paul, OP da Costa, M Ritter… - Journal of allergy and …, 2014 - Elsevier
Background Schistosomiasis, a chronic helminth infection, elicits distinct immune responses
within the host, ranging from an initial TH 1 and subsequent TH 2 phase to a regulatory …

Influence of schistosomiasis on host vaccine responses

JK Nono, SD Kamdem, F Musaigwa, CA Nnaji… - Trends in …, 2022 - cell.com
Schistosomiasis is a debilitating helminthiasis which commonly establishes as a chronic
infection in people from endemic areas. As a potent modulator of the host immune response …

Maternal Schistosomiasis japonica is associated with maternal, placental, and fetal inflammation

JD Kurtis, A Higashi, HW Wu, F Gundogan… - Infection and …, 2011 - Am Soc Microbiol
Schistosomes infect∼ 40 million women of childbearing age and result in the elaboration of
proinflammatory cytokines that have been implicated in fetal growth restriction. In murine …

Recent advances and methodological considerations on vaccine candidates for human schistosomiasis

U Panzner, JL Excler, JH Kim, F Marks… - Frontiers in Tropical …, 2021 - frontiersin.org
Schistosomiasis remains a neglected tropical disease of major public health concern with
high levels of morbidity in various parts of the world. Although considerable efforts in …

Prevalence and risk factors of Schistosoma mansoni infection among children under two years of age in Mbita, Western Kenya

M Sassa, EA Chadeka, NB Cheruiyot… - PLoS neglected …, 2020 - journals.plos.org
Despite growing evidence that infants and very young children can be infected with
schistosomes, the epidemiological features and risk factors are not well described in this …