The increasing prevalence of diabetes and its complications, such as cardiovascular and
kidney disease, remains a huge burden globally. Identification of biomarkers for the …

Globally, diabetes is the leading cause of chronic kidney disease and end-stage renal
disease, which are major risk factors for cardiovascular disease and death. Despite this …

Diabetic kidney disease (DKD) remains one of the leading causes of reduced lifespan in
diabetes. The quest for both prognostic and surrogate endpoint biomarkers for advanced …

Diabetic kidney disease, commonly termed diabetic nephropathy (DN), is the most common
cause of end-stage kidney disease (ESKD) worldwide. The characteristic histopathology of …

Chronic kidney disease (CKD), characterized as renal dysfunction, is recognized as a major
public health problem with high morbidity and mortality worldwide. Unfortunately, there are …

Diabetic retinopathy (DR) is the main cause of vision loss or blindness in working age adults
worldwide. The lack of effective diagnostic biomarkers for DR leads to unsatisfactory curative …

BACKGROUND Metabolomic profiling in individuals with chronic kidney disease (CKD) has
the potential to identify novel biomarkers and provide insight into disease pathogenesis …

Aims/hypothesis This prospective, observational study examines associations between 51
urinary metabolites and risk of progression of diabetic nephropathy in individuals with type 1 …

Diabetic kidney disease (DKD) is a leading cause of end-stage renal disease (ESRD).
Although both albuminuria and glomerular filtration rate (GFR) are well-established …

Background and Aims Acute kidney injury (AKI) has a poor prognosis in cirrhosis. Given the
variability of creatinine, the prediction of AKI and dialysis by other markers is needed. The …