A coalition to heal—the impact of the cardiac microenvironment

E Tzahor, S Dimmeler - Science, 2022 - science.org
Heart regenerative medicine has been gradually evolving from a view of the heart as a
nonregenerative organ with terminally differentiated cardiac muscle cells. Understanding the …

Differential regulation of lymphatic junctional morphology and the potential effects on cardiovascular diseases

AM Peluzzo, M Bkhache, LNH Do, MV Autieri… - Frontiers in …, 2023 - frontiersin.org
The lymphatic vasculature provides an essential route to drain fluid, macromolecules, and
immune cells from the interstitium as lymph, returning it to the bloodstream where the …

Regulation and impact of cardiac lymphangiogenesis in pressure-overload-induced heart failure

C Heron, A Dumesnil, M Houssari… - Cardiovascular …, 2023 - academic.oup.com
Aims Lymphatics are essential for cardiac health, and insufficient lymphatic expansion
(lymphangiogenesis) contributes to development of heart failure (HF) after myocardial …

Lymphatic endothelial sphingosine 1-phosphate receptor 1 enhances macrophage clearance via lymphatic system following myocardial infarction

Q Li, C Zhou, K Zhao, Y Duan, J Yue, X Liu… - Frontiers in …, 2022 - frontiersin.org
Lymphatic endothelial cell homeostasis plays important roles in normal physiological
cardiac functions, and its dysfunction significantly influences pathological cardiac …

Lymphatic trafficking of immune cells and insights for cancer metastasis

DG Jackson - Clinical & Experimental Metastasis, 2024 - Springer
Most cancers and in particular carcinomas metastasise via the lymphatics to draining lymph
nodes from where they can potentially achieve systemic dissemination by invasion of high …

The multifaceted nature of endogenous cardiac regeneration

L Rolland, C Jopling - Frontiers in Cardiovascular Medicine, 2023 - frontiersin.org
Since the first evidence of cardiac regeneration was observed, almost 50 years ago, more
studies have highlighted the endogenous regenerative abilities of several models following …

Tumor microenvironment restricts IL-10 induced multipotent progenitors to myeloid-lymphatic phenotype

L Volk-Draper, S Athaiya, M Espinosa Gonzalez… - Plos one, 2024 - journals.plos.org
Lymphangiogenesis is induced by local pro-lymphatic growth factors and bone marrow (BM)-
derived myeloid-lymphatic endothelial cell progenitors (M-LECP). We previously showed …

[HTML][HTML] 心脏淋巴系统与心肌梗死后心肌修复的研究进展

邓廷玉, 石兆丰, 肖宜超 - Journal of Central South University …, 2023 - ncbi.nlm.nih.gov
心脏淋巴系统在心肌损伤后修复过程中发挥重要作用, 其可能通过维持体液稳态和控制炎症
反应来调控正常组织稳态和自然再生。 心脏淋巴系统在心肌损伤后激活并参与心脏疤痕形成 …

Cardiac lymphatics: state of the art

C Heron, A Ratajska, E Brakenhielm - Current Opinion in …, 2022 - journals.lww.com
Recent years have witnessed a significant expansion in our knowledge of the molecular
characteristics and regulation of cardiac lymphatics. The current body of work is in support of …

Research progress in the cardiac lymphatic system and myocardial repair after myocardial infarction.

T Deng, Z Shi, Y Xiao - Zhong nan da xue xue bao. Yi xue ban …, 2023 - europepmc.org
心脏淋巴系统在心肌损伤后修复过程中发挥重要作用, 其可能通过维持体液稳态和控制炎症反应
来调控正常组织稳态和自然再生. 心脏淋巴系统在心肌损伤后激活并参与心脏疤痕形成进程 …