Radiation-induced lung injury: assessment and management

AN Hanania, W Mainwaring, YT Ghebre, NA Hanania… - Chest, 2019 - Elsevier
Radiation-induced lung injury (RILI) encompasses any lung toxicity induced by radiation
therapy (RT) and manifests acutely as radiation pneumonitis and chronically as radiation …

Automatic planning of head and neck treatment plans

I Hazell, K Bzdusek, P Kumar… - Journal of applied …, 2016 - Wiley Online Library
Treatment planning is time‐consuming and the outcome depends on the person performing
the optimization. A system that automates treatment planning could potentially reduce the …

Relationship between prior radiotherapy and checkpoint-inhibitor pneumonitis in patients with advanced non–small-cell lung cancer

KR Voong, SZ Hazell, W Fu, C Hu, CT Lin, K Ding… - Clinical lung cancer, 2019 - Elsevier
Purpose To investigate the relationship between radiotherapy (RT), in particular chest RT,
and development of immune-related (IR) pneumonitis in non–small-cell lung cancer …

Incidence, risk factors, and CT characteristics of radiation recall pneumonitis induced by immune checkpoint inhibitor in lung cancer

F Cousin, C Desir, SB Mustapha, C Mievis… - Radiotherapy and …, 2021 - Elsevier
Background and purpose Radiation recall pneumonitis (RRP) is a delayed radiation-
induced lung toxicity triggered by systemic agents, typically anticancer drugs. Immune …

Deformable image registration applied to lung SBRT: Usefulness and limitations

D Sarrut, T Baudier, M Ayadi, R Tanguy, S Rit - Physica Medica, 2017 - Elsevier
Radiation therapy (RT) of the lung requires deformation analysis. Deformable image
registration (DIR) is the fundamental method to quantify deformations for various …

Mechanistic model of radiotherapy-induced lung fibrosis using coupled 3D agent-based and Monte Carlo simulations

N Cogno, R Bauer, M Durante - Communications Medicine, 2024 - nature.com
Background Mechanistic modelling of normal tissue toxicities is unfolding as an alternative
to the phenomenological normal tissue complication probability models. The latter, currently …

Compound Kushen Injection Reduces Severe Toxicity and Symptom Burden Associated With Curative Radiotherapy in Patients With Lung Cancer

J Liu, Q Yu, XS Wang, Q Shi, J Wang, F Wang… - Journal of the National …, 2023 - jnccn.org
Background: Radiotherapy (RT) causes adverse events for which there are no effective
treatments. This study investigated the clinical benefits of compound Kushen injection (CKI) …

Inclusion of functional information from perfusion SPECT improves predictive value of dose–volume parameters in lung toxicity outcome after radiotherapy for non …

KP Farr, JF Kallehauge, DS Møller, AA Khalil… - Radiotherapy and …, 2015 - Elsevier
Background and purpose To compare functional and standard dose–volume parameters as
predictors of postradiation pulmonary toxicity in lung cancer patients undergoing curative …

CT characteristics allow identification of patient-specific susceptibility for radiation-induced lung damage

G Defraene, W van Elmpt, W Crijns… - Radiotherapy and …, 2015 - Elsevier
Background and purpose There is a huge difference in radiosensitivity of lungs between
patients. The present study aims to identify and quantify patient-specific radiosensitivity …

The dose–response characteristics of four NTCP models: using a novel CT-based radiomic method to quantify radiation-induced lung density changes

D Begosh-Mayne, SS Kumar, S Toffel, P Okunieff… - Scientific Reports, 2020 - nature.com
Multiple competing normal tissue complication probability (NTCP) models have been
proposed for predicting symptomatic radiation-induced lung injury in human. In this paper …