Pancreatic cancer: pathogenesis, screening, diagnosis, and treatment

LD Wood, MI Canto, EM Jaffee, DM Simeone - Gastroenterology, 2022 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) is a clinically challenging cancer, due to both its
late stage at diagnosis and its resistance to chemotherapy. However, recent advances in our …

AGA clinical practice update on pancreas cancer screening in high-risk individuals: expert review

HR Aslanian, JH Lee, MI Canto - Gastroenterology, 2020 - Elsevier
Description The purpose of this American Gastroenterological Association Institute Clinical
Practice Update is to describe the indications for screening for pancreas cancer in high-risk …

The management of Peutz–Jeghers syndrome: European hereditary tumour group (EHTG) guideline

A Wagner, S Aretz, A Auranen, MJ Bruno… - Journal of clinical …, 2021 - mdpi.com
The scientific data to guide the management of Peutz–Jeghers syndrome (PJS) are sparse.
The available evidence has been reviewed and discussed by diverse medical specialists in …

Pancreatic cancer surveillance and survival of high-risk individuals

AL Blackford, MI Canto, M Dbouk, RH Hruban… - JAMA …, 2024 - jamanetwork.com
Importance Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease with increasing
incidence. The majority of PDACs are incurable at presentation, but population-based …

The Role of BRCA Testing in Hereditary Pancreatic and Prostate Cancer Families

R Pilarski - American Society of Clinical Oncology Educational …, 2019 - ascopubs.org
Beyond breast and ovarian cancers, mutations in the BRCA1 and BRCA2 genes increase
risks for pancreatic and prostate cancers and contribute to the prevalence of these cancers …

[HTML][HTML] Current epidemiology of pancreatic cancer: Challenges and opportunities

W Luo, J Tao, L Zheng, T Zhang - Chinese Journal of Cancer …, 2020 - ncbi.nlm.nih.gov
Pancreatic cancer (PC) is an increasingly common disease worldwide. Having a better
understanding of worldwide and regional epidemiologic features and risk factors of PC is …

Late-stage pancreatic cancer detected during high-risk individual surveillance: a systematic review and meta-analysis

A Chhoda, Z Vodusek, K Wattamwar, E Mukherjee… - Gastroenterology, 2022 - Elsevier
Background & Aims Identification and resection of successful targets, that is, T 1 N 0 M 0
pancreatic ductal adenocarcinoma (PDAC) and high-grade precursors during surveillance …

Clinical risk management of breast, ovarian, pancreatic, and prostatic cancers for BRCA1/2 variant carriers in Japan

A Ueki, R Yoshida, T Kosaka… - Journal of Human …, 2023 - nature.com
Opportunities for genetic counseling and germline BRCA1/2 (BRCA) testing are increasing
in Japan owing to cancer genomic profiling testing and companion diagnostics being …

Familial pancreatic cancer

H Saba, M Goggins - Gastroenterology Clinics, 2022 - gastro.theclinics.com
Pancreatic ductal adenocarcinoma (PDAC) is the deadliest of all major cancer types with
most patients having advanced disease at diagnosis. Recent data from the National Cancer …

Recommendations for a more organized and effective approach to the early detection of pancreatic cancer from the PRECEDE (pancreatic cancer early detection) …

TA Gonda, JN Everett, M Wallace, DM Simeone… - …, 2021 - gastrojournal.org
Implementation of an effective screening test requires identification of a target population.
Because of its relatively low incidence, sensitivity and specificity levels of existing …