Machine intelligence in peptide therapeutics: A next‐generation tool for rapid disease screening

S Basith, B Manavalan, T Hwan Shin… - Medicinal research …, 2020 - Wiley Online Library
Discovery and development of biopeptides are time‐consuming, laborious, and dependent
on various factors. Data‐driven computational methods, especially machine learning (ML) …

Antioxidant and antimicrobial peptides derived from food proteins

G López-García, O Dublan-García, D Arizmendi-Cotero… - Molecules, 2022 - mdpi.com
Recently, the demand for food proteins in the market has increased due to a rise in
degenerative illnesses that are associated with the excessive production of free radicals and …

DRAMP 3.0: an enhanced comprehensive data repository of antimicrobial peptides

G Shi, X Kang, F Dong, Y Liu, N Zhu, Y Hu… - Nucleic acids …, 2022 - academic.oup.com
Stapled antimicrobial peptides are an emerging class of artificial cyclic peptide molecules
which have antimicrobial activity and potent structure stability. We previously published the …

dbAMP 2.0: updated resource for antimicrobial peptides with an enhanced scanning method for genomic and proteomic data

JH Jhong, L Yao, Y Pang, Z Li, CR Chung… - Nucleic acids …, 2022 - academic.oup.com
The last 18 months, or more, have seen a profound shift in our global experience, with many
of us navigating a once-in-100-year pandemic. To date, COVID-19 remains a life …

iAtbP-Hyb-EnC: Prediction of antitubercular peptides via heterogeneous feature representation and genetic algorithm based ensemble learning model

S Akbar, A Ahmad, M Hayat, AU Rehman… - Computers in Biology …, 2021 - Elsevier
Tuberculosis (TB) is a worldwide illness caused by the bacteria Mycobacterium tuberculosis.
Owing to the high prevalence of multidrug-resistant tuberculosis, numerous traditional …

Machine learning prediction of antimicrobial peptides

G Wang, II Vaisman, ML van Hoek - Computational peptide science …, 2022 - Springer
Antibiotic resistance constitutes a global threat and could lead to a future pandemic. One
strategy is to develop a new generation of antimicrobials. Naturally occurring antimicrobial …

iAMPCN: a deep-learning approach for identifying antimicrobial peptides and their functional activities

J Xu, F Li, C Li, X Guo, C Landersdorfer… - Briefings in …, 2023 - academic.oup.com
Antimicrobial peptides (AMPs) are short peptides that play crucial roles in diverse biological
processes and have various functional activities against target organisms. Due to the abuse …

pAtbP-EnC: identifying anti-tubercular peptides using multi-feature representation and genetic algorithm based deep ensemble model

S Akbar, A Raza, T Al Shloul, A Ahmad, A Saeed… - IEEE …, 2023 - ieeexplore.ieee.org
Mycobacterium tuberculosis, a highly perilous pathogen in humans, serves as the causative
agent of tuberculosis (TB), affecting nearly 33% of the global population. With the increasing …

In silico Approaches for the Design and Optimization of Interfering Peptides Against Protein–Protein Interactions

ZS Hashemi, M Zarei, MK Fath, M Ganji… - Frontiers in Molecular …, 2021 - frontiersin.org
Large contact surfaces of protein–protein interactions (PPIs) remain to be an ongoing issue
in the discovery and design of small molecule modulators. Peptides are intrinsically capable …

[HTML][HTML] AtbPpred: a robust sequence-based prediction of anti-tubercular peptides using extremely randomized trees

B Manavalan, S Basith, TH Shin, L Wei… - Computational and …, 2019 - Elsevier
Mycobacterium tuberculosis is one of the most dangerous pathogens in humans. It acts as
an etiological agent of tuberculosis (TB), infecting almost one-third of the world's population …