Cellular senescence and the senescence-associated secretory phenotype (SASP) are
implicated in aging and age-related disease, and SASP-related inflammation is thought to …

Formins are proteins that catalyze the formation of linear filaments made of actin. INF2, a
formin, is crucial for correct vesicular transport, microtubule stability and mitochondrial …

Ovarian cancer (OC) is a highly malignant cancer with great metastatic potential. Here we
aimed to investigate the role of Piezo1, a gene related to the mechanical environment of the …

Yes‐associated protein (YAP) and its homologue TAZ are transducers of several
biochemical and biomechanical signals, integrating multiplexed inputs from the …

The Hippo signaling pathway regulates tissue growth and cell fate, and its dysregulation can
induce tumorigenesis. When Hippo is activated by cell–cell contact, extracellular signals, or …

Neuromedin S (NMS) plays key roles in reproductive regulation, while its function and
mechanism in follicular development remain unclear. The current study aims to investigate …

Intestinal organoids represent a three-dimensional cell culture system mimicking the
mammalian intestine. The application of single-cell ablation for defined wounding via a …

Polyglutamine (polyQ) induced neurodegeneration is one of the leading causes of
progressive neurodegenerative disorders characterized clinically by deteriorating movement …

Simple Summary Rumen development is important to the health and performance of
ruminants. The proteins YAP1 and TAZ are key regulators of the mammalian epithelium …

Yorkie (Yki) is a key effector of the Hippo pathway that activates the expression of targets by
associating with the transcription factor Scalloped (Sd). Various upstream signals, such as …