Heavy alcohol consumption is a major cause of morbidity and mortality. Globally, alcohol per-
capita consumption rose from 5.5 litres in 2005 to 6.4 litres in 2016 and is projected to …

There is still an unresolved paradox with respect to the immunomodulating role of estrogens.
On one side, we recognize inhibition of bone resorption and suppression of inflammation in …

Liver damage ranges from acute hepatitis to hepatocellular carcinoma, through apoptosis,
necrosis, inflammation, immune response, fibrosis, ischemia, altered gene expression and …

Heavy alcohol use is the cause of alcoholic liver disease (ALD). The ALD spectrum ranges
from alcoholic steatosis to steatohepatitis, fibrosis, and cirrhosis. In Western countries …

Alcohol is one of the main causes of end-stage liver disease worldwide, and alcoholic liver
disease is the second most common reason for liver transplantation in the United States …

Acute liver failure (ALF) is a syndrome of diverse aetiology, including hepatic
encephalopathy, renal, cardiac and pulmonary failures, which result in a rapid loss of …

Abstract Background & Aim. Non alcoholic fatty liver disease (NAFLD) is the most common
liver disease in Western countries. Population studies have demonstrated that men and …

Background: Recent advances in the field of acetaldehyde (AcH) research have raised the
need for a comprehensive review on the role of AcH in the actions of alcohol. This update is …

Both chronic and acute (binge) alcohol drinking are important health and economic
concerns worldwide and prominent risk factors for the development of alcoholic liver disease …

This article discusses several subjects pertinent to a consideration of the role of gender and
hormones in alcoholic liver injury (ALI). Beginning with an overview of factors involved in the …